On this episode I discuss chlorthalidone pharmacology, adverse effects, and recent literature regarding cardiovascular disease reduction. Our friends at Pyrls.com are offering a free diagram of the nephron including the mechanism of action AND a summary of diuretic effects that I discussed on the podcast - Go sign up and get these for free and support this a ... Show More
Nov 20
Glycopyrrolate Pharmacology
Glycopyrrolate is an anticholinergic medication commonly used to reduce excessive secretions, particularly in palliative care, postoperative settings, and certain neurologic conditions. It works by blocking acetylcholine at muscarinic receptors, which decreases salivary and respi ... Show More
11m 47s
Nov 13
Bisacodyl (Dulcolax) Pharmacology
Bisacodyl, commonly known by the brand name Dulcolax, is a stimulant laxative widely used for short-term relief of constipation and bowel preparation before procedures. It works by directly stimulating the enteric nerves in the colon, increasing peristalsis, and promoting bowel e ... Show More
15m 53s
Mar 2022
REBOOT #145 Hepatorenal Syndrome
Tackle the complex pathophysiology, diagnosis, and management of hepatorenal syndrome in this Curbsiders classic from #NephMadness 2019 featuring @kidney_boy Joel Topf, HRS expert Juan Carlos Velez (@veleznephhepato), and self-proclaimed most-handsome-nephrologist Bill Whittier ( ... Show More
1h 8m
Nov 2021
#308 Metabolic Alkalosis and Hypokalemia: Kidney Boy Returns!
@Kidney_Boy returns to school us on metabolic alkalosis and hypokalemia! What do diuretics, hyperaldosteronism, black licorice, and milk-alkali have in common? Our Chief of Nephrology, Dr. Joel Topf, talks through the pathophysiology of metabolic alkalosis, the utility of urine c ... Show More
1h 9m
Aug 2022
Is Pharmacology Difficult Podcast ATROPINE & ALTERNATIVE DRUGS/SUBSTITUTES-5 AND ATROPINE POISONING
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.A quick, celebrated poetic August weather update will break the ice today!!In this episode, I will be discussing Atropine poisoning, its diagnosis and cure. But before that I will quickly cover points related ... Show More
17m 6s
Mar 2022
#326 Cardiorenal Syndrome, Biomarkers, Diuretic Resistance (NephMadness 2022)
Lose your heart to NephMadness 2022! Dr. Joel Topf (@kidney_boy) and Dr. Sadiya Khan (@HeartDocSadiya) tackle the NephMadness 2022 Cardiorenal Syndrome region, leading us through the pathophysiology of cardiorenal syndrome, how to approach the creatinine “bump” with diuresis, man ... Show More
56m 35s
Jun 2023
310. Guidelines: 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure – Question #23 with Dr. Anu Lala
The following question refers to Section 9.3 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.The question is asked by Keck School of Medicine USC medical student & CardioNerds Intern Hirsh Elhence, answered first by Cedars Sinai medicine resident, soon to b ... Show More
18m 27s
Aug 2022
The Surprising Truth of Uric Acid and How It Impacts Metabolic Health with Dr. David Perlmutter
This episode is brought to you by InsideTracker and Gut Food. Researchers around the globe over the past decade have discovered that uric acid, previously thought of only in terms of gout, actually plays a central role in metabolic disorders. So, how is uric acid orchestrating th ... Show More
40m 24s
Jun 2023
Pharmacology of Peptic Ulcer Disease [#DaVinciCases GI 9 - Pharmacology Case 1]
This case covers the mechanisms of action, side effects, and relevant physiology for medications used to treat peptic ulcer disease. The corresponding video is on YouTube (https://youtu.be/0l1mmJafU3w). **Thank you to our sponsor Doc2Doc Lending, the Personal Lending platform des ... Show More
7m 35s