In this episode, we welcome Jake Rubens, a seasoned genomic science entrepreneur and co-founder of Quotient Therapeutics. Tune in to hear Jake discuss the potential of somatic genomics (genes that are present in any cell in the body except for germline cells) in therapeutic development. As the founder of several companies, including Tessera and Sana Therapeu ... Show More
Aug 21
EP 201: The gene therapy playbook: Successes, setbacks, and the path forward with Richard Wilson of Astellas
This week on The Genetics Podcast, Patrick is joined by Richard Wilson, Senior Vice President, Primary Focus Lead of Genetic Regulation at Astellas. They discuss where the gene therapy field stands today, diving into successes, persistent barriers, regulatory considerations, manu ... Show More
47m 28s
Aug 14
EP 200: From predictions to breakthroughs in genetics and biotech
This week on The Genetics Podcast, we celebrate our 200th episode with a look back at some of the earliest episodes, particularly ones that foresaw major trends or went on to spark real-world impact. These include Eric Topol’s early predictions about AI in healthcare, Laurence Re ... Show More
34m 40s
Aug 7
EP 199: Functional genomics at scale: Using in vivo perturbations to study genetic risk variants in the brain with Xin Jin of Scripps Research Institute
This week on The Genetics Podcast, Patrick is joined by Xin Jin, Associate Professor in the Department of Neuroscience at The Scripps Research Institute. They discuss how in vivo Perturb-seq enables scalable and high-resolution modeling of neurogenetic disorders like autism, how ... Show More
36m 31s
Feb 2023
Dr. Oded Rechavi: Genes & the Inheritance of Memories Across Generations
In this episode, my guest is Oded Rechavi, Ph.D., professor of neurobiology at Tel Aviv University and expert in how genes are inherited, how experiences shape genes and remarkably, how some memories of experiences can be passed via genes to offspring. We discuss his research cha ... Show More
2h 27m
Aug 2023
#268 ‒ Genetics: testing, therapy, editing, association with disease risk, autism, and more | Wendy Chung, M.D., Ph.D.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter Wendy Chung is a board-certified clinical and molecular geneticist with more than 25 years of experience in human genetic disease research. In this ... Show More
2h 27m
Jul 2017
Genomics, Machine Learning, and the Future of Big Data in Medicine | Eric Schadt
In Episode 15 of Hidden Forces, host Demetri Kofinas speaks with Dr. Eric Schadt. Eric Schadt is founder and CEO of Sema4, as well as Dean of Precision Medicine at the Icahn School of Medicine at Mount Sinai. During the course of his 20-year career, Dr. Eric Schadt has built gene ... Show More
1h 4m
Dec 2023
Coleen T. Murphy, "How We Age: The Science of Longevity" (Princeton UP, 2023)
All of us would like to live longer, or to slow the debilitating effects of age. In How We Age: The Science of Longevity (Princeton UP, 2023), Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging ... Show More
31m 35s