Summary and discussion of MIRACL and PRO...

For full review of the trials, please visit https://cardiologytrials.substack.com/ Get full access to Cardiology Trial’s Substack at cardiologytrials.substack.com/subscribe 

N Engl J Med 2004;351:2049-2057Background: Endothelial dysfunction, reduced nitric oxide availability, and increased oxidative stress occur in patients with heart failure and contribute to cardiac remodeling. In the V-HeFT I trial, combining isosorbide dinitrate (a nitric oxide d ... Show More

THE LANCET 2003;362:772-776Background: Angiotensin converting enzyme inhibitors (ACEi) reduce mortality and morbidity in patients with systolic heart failure (see CONSENSUS and SOLVD trials). However, registry data showed that up to 20% of patients with systolic heart failure wer ... Show More

Jerry presents with a history of myocardial infarction and reports experiencing chest pain during exercise. Which of the following interventions would be MOST appropriate? A. Discontinue exercise immediately and refer the patient to a physician B. Continue exercise at a reduced i ... Show More

Clues in SCAF, a DOAC antidote trial, another negative lytic trial in stroke, JAMA changes to observational studies, and BP in stroke care are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partia ... Show More

Diets, coronary artery calcium, statins, basic CAD knowledge, and AF ablation are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.co ... Show More

CardioNerds cofounders, Dan Ambinder joins Drs. Aishwarya Pastapur, Oyinkansola Osobamiro, and Rafik Issa from the University of Michigan for drinks in Ann Arbor. They discuss the following case of pericardial decompression syndrome. Expert commentary is provided by Dr. Brett Wan ... Show More

CardioNerds (Amit Goyal & Daniel Ambinder) join Brown University cardiology fellows (Greg Salber, Vrinda Trivedi, and Esseim Sharma) for a gorgeous coastal boat ride in Providence, RI. They discuss an educational case of hypertrophic cardiomyopathy with superimposed stress cardio ... Show More

In today's episode, we delve into the intricate world of cardiovascular health. We will explore a myriad of complications spanning from within the heart itself to the peripheral vasculature. Our discussion will encompass various vascular diseases, such as carotid artery sten ... Show More

When to use an ICD, risk stratification for HCM, blending EP and structural cardiology to improve care in post-TAVI patients, and hsTroponins are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a ... Show More

The cardiac OR can be a daunting place for any medical student or resident who finds themself on a cardiac surgery rotation. Have no fear, this Cardiac Surgery Crash Course is a short series focused on high-yield topics to help introduce students and residents to cardiac surgery ... Show More

In this episode I cover cardiovascular disease. If you want to follow along with written notes on cardiovascular disease go to zerotofinals.com/cvd or find the cardiology section in the Zero to Finals medicine book. This episode covers the pathophysiology of atherosclerosis, the ... Show More

Dr. Fatimah Alkhunaizi and the CardioNerds discuss a case of hypertrophic cardiomyopathy, covering pathophysiology, diagnosis, imaging, and management of HCM. Show notes and images: https://www.cardionerds.com/hypertrophic-cardiomyopathy/