One week ago, Matthew Perry’s autopsy report came back, finding that the ‘Friends’ actor died from the acute effects of ketamine overdose. His death has sharpened focus on the popular and controversial drug. Ketamine has been hailed as a miracle cure for depression and anxiety, criticized as a VC-fueled fad, and investigated as a placebo. But what is ketamin ... Show More
Jun 9
How Modern Fatherhood Is Changing Men’s Brains
Humans are unusual dads. Across the animal kingdom, dads are often absent from child-rearing altogether. But among humans, fatherhood takes many forms, and in the last half century, it has changed dramatically. College-educated American fathers now spend nearly four times as much ... Show More
1h 4m
Jun 5
What 400,000 Essays Reveal About AI and Creativity
For generations, we've defined creativity by its products: the novel, the painting, the song, the breakthrough idea. We look at the work, and from the work we see the creator as “creative.” But AI is getting remarkably good at producing creative work. In some cases, experts now p ... Show More
56m 2s
Jun 2
The Surprising Truth About America's Friendship Crisis
Modern loneliness is often treated as a simple problem: People are simply spending more time alone. But what if that's not the whole story? Over the last several years, Derek has written about workism, the rise of a culture that puts work at the center of our lives, and the "anti ... Show More
58m 53s
Dec 2024
Your Brain On... Ketamine
<p dir="ltr"><strong>For decades, ketamine has mainly been used as an anaesthetic, but in more recent years, it's gained popularity in mental health treatment.</strong></p> <p dir="ltr">Conversations around the benefits and risks associated with its therapeutic usage ignited towa ... Show More
44m 45s
May 2025
How Ketamine is Changing Depression Treatment – Dr. John Krystal Explains
Dr. John Krystal, a leading psychiatrist and neuroscientist, explains how ketamine works in the brain, why it’s revolutionizing depression treatment, and what the future holds for psychedelic-assisted therapy. His journey to discovering the revolutionary benefits of Ketamine trea ... Show More
21m 7s
Aug 2025
Will psychedelics revolutionize mental health treatment? | Matthew Johnson, Shayla Love, and Kevin Sabet
<p><strong>The psychedelic revolution</strong></p><p>Will LSD, Psilocybin, MDMA, and Ketamine treatments live up to the hype?</p><p>For decades, psychedelics were derided as dangerous recreational drugs; now many claim they have the potential to revolutionise the treatment of men ... Show More
49m 34s
Apr 2022
Ketamine & Psychedelic Psychotherapy with Dr. Steve Thayer
In this episode Michelle interviews Dr. Steve Thayer, a clinical psychologist at Cedar Psychiatry, about his work using psychotherapy in conjunction with ketamine, a legal and safe psychedelic substance. Michelle shares her personal experience with Dr. Thayer when she participate ... Show More
48m 7s