Some of the most basic questions about ketamine are still under investigation— Which patients are ideal responders? What is the therapeutic dose range? Is there a meaningful dose/response curve? Are fully dissociative treatments necessary for optimal efficacy? How important is psychotherapy after a higher dose IV or IM session? And how should we think about ... Show More
Today
GLP-1s, Eating Disorders, and Body Image with Dr. Jennifer Gaudiani
Are GLP-1s the best thing to come along in psychiatry in years…. or are they going to turn out to have a dark side, by triggering eating disorders, causing undernutrition, and narrowing what’s an acceptable body type? Dr. H sits down with nationally known eating disorder speciali ... Show More
1h 4m
Sep 25
The legacy of institutionalization-- Orphanages, attachment trauma, borderline personality disorder, and C-PTSD
This is the story of Milena, starting with her early years in a Bulgarian orphanage, then the hope and promise of being adopted by an American family, and finally the emerging and increasingly ominous consequences of early attachment trauma and institutionalization. Adoption is c ... Show More
1h 6m
May 2025
How Ketamine is Changing Depression Treatment – Dr. John Krystal Explains
Dr. John Krystal, a leading psychiatrist and neuroscientist, explains how ketamine works in the brain, why it’s revolutionizing depression treatment, and what the future holds for psychedelic-assisted therapy. His journey to discovering the revolutionary benefits of Ketamine trea ... Show More
20m 37s
Aug 2023
Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
In this episode, I explain how ketamine causes rewiring of brain circuits and dissociative states to relieve symptoms of depression and post-traumatic stress disorder (PTSD). I explain how ketamine impacts both the brain’s glutamate and its endogenous opioid pathways, which toget ... Show More
1h 38m
Apr 2023
Episode 346: Electroconvulsive Therapy vs Ketamine. Which is better?
<div data-pm-slice="1 1 []" data-en-clipboard="true"> <span data-highlight="green">Hello, friends! In this episode, I tackle one awesome question from a listener. This person has treatment resistant depression and bipolar. Their mania is well-controlled, but they need a higher le ... Show More
27m 36s
Apr 2023
Ketamine: How Special is Special K?
For years, ketamine has been thought of mostly as a horse tranquilizer — or a street drug that puts you in a scary-sounding K-hole. But now, we’re hearing reports that it could be almost a miracle medicine, treating stubborn depression and other mental illnesses. So how good is i ... Show More
32m 16s
Apr 2022
Ketamine & Psychedelic Psychotherapy with Dr. Steve Thayer
In this episode Michelle interviews Dr. Steve Thayer, a clinical psychologist at Cedar Psychiatry, about his work using psychotherapy in conjunction with ketamine, a legal and safe psychedelic substance. Michelle shares her personal experience with Dr. Thayer when she participate ... Show More
48m 7s
<p dir="ltr"><strong>Contributor: Travis Barlock MD</strong></p> <p dir="ltr"><strong>Educational Pearls:</strong></p> <p dir="ltr">Ketamine is an NMDA receptor antagonist with a wide variety of uses in the emergency department. To dose ketamine remember the numbers 0.3, 1, and 3 ... Show More
