In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and talks with the investigator who developed the “off-the-shelf” CAR T cells that made her treatment possible.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp23 ... Show More
Jul 2023
The Plight of Primary Care, Part 1
This episode of “Intention to Treat,” explores the crisis in primary care in the United States, as increasing numbers or primary care physicians leave the field — driven out by corporatization, growing time pressure, and the inability to form the relationships that enable good ca ... Show More
54m 55s
Sep 2020
Immunotherapy: Transforming How Cancers Are Treated
In this episode, Dr. Diane Reidy-Lagunes talks to medical oncologist and scientist Dr. Jedd Wolchok and cancer survivor Grace Dunn. Together, they help decode the emerging new defense against cancer: immunology. For more information or to ask a question, please visit MSKCC.org/po ... Show More
23m 44s
Aug 2024
CAR T-cell Therapy in AML: State of the Art
Tune in to our podcast for an in-depth discussion on immunotherapeutic strategies for Acute Myeloid Leukemia (AML). In this episode, we feature Dr Sarah Tettamanti, a senior scientist at the Fondazione Tettamanti Research Centre in Italy, who shares her expertise on CAR T-cell th ... Show More
15m 1s
Apr 2022
Structural racism and AML survival, promoter competition and hemoglobin switching, and CAR T-cell therapy and high-risk cytogenetics in ALL
In this week’s episode we’ll first cover a research article demonstrating the striking contribution of neighborhood disadvantage to racial and ethnic disparities in survival in patients with acute myeloid leukemia. The second research article provides a model for understanding ho ... Show More
17m 55s
Mar 2024
India’s Breakthrough in Cancer Cure
<p>Thejna John is a happy woman. Last year, the relapse of an acute form of blood cancer despite a bone marrow transplant, had made her doctors give up all hope.</p> <p>In October, came a breakthrough. India approved the CAR T-Cell therapy, a revolutionary treatment for some form ... Show More
30m 1s