In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and talks with the investigator who developed the “off-the-shelf” CAR T cells that made her treatment possible.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp23 ... Show More
Jul 2023
The Plight of Primary Care, Part 1
This episode of “Intention to Treat,” explores the crisis in primary care in the United States, as increasing numbers or primary care physicians leave the field — driven out by corporatization, growing time pressure, and the inability to form the relationships that enable good ca ... Show More
54m 55s
Jul 2024
Episode 108: Colorectal Cancer Series, Pt. 10 - Metastatic Colorectal Cancer (Part 2)
<p>This week, we round out our discussion on metastatic colorectal cancer, focusing on more targeted therapies for this disease. If you have not done so already, be sure to check out episode 107 for the first part of our metastatic colorectal cancer discussion.</p><p>Contents: </ ... Show More
24m 34s
Jul 2024
Episode 107: Colorectal Cancer Series, Pt. 9 - Metastatic Colorectal Cancer (Part 1)
<p>This week, we continue our discussion of colorectal cancer, turning our attention to metastatic disease, specifically for cancers without targetable mutations. If you have not done already, we highly recommend you check out episode 104 for our GI oncology pharmacology discussi ... Show More
34m 37s
Apr 2021
Ep. 2: “A Tale of Three Sisters” Featuring Drs. Mindy, Amy, and Kristen Engevik
Guests: Drs. Mindy, Amy, and Kristen Engevik are sisters and immunologists. Dr. Mindy Engevik is an Assistant Professor at the Medical University of South Carolina. Her lab studies microbial-host crosstalk with an emphasis on microbe-mucus interactions. Dr. Amy Engevik is also an ... Show More
1h 13m
Jun 2024
Episode 106: Colorectal Cancer Series, Pt. 8 - Early Onset Colorectal Cancer
<p>In a recent American Cancer Society publication, there are increasing data that rates of colorectal cancer are rising rapidly among people in their 20s, 30s and 40s. This has certainly caught the attention of the lay press, most recently in a widely circulated New York Times a ... Show More
30m 34s
Dec 2024
141. Back to Basics - The role of endocrine therapy in Breast Cancer
<p>Before immunotherapy, targeted chemotherapy (ADCs) and precision oncology, there was endocrine therapy, the forefather (or mother) of effective treatment to reduce breast cancer recurrence as well as delay disease progression. This episode dives into a past of phenomenal impro ... Show More
24m 4s