David Gornoski moderates a debate between Tucker Goodrich and Brad Marshall on whether oleic acid should be consumed. Now that all the evidence points to seed oils being extremely damaging to our health, the question revolves around what's the best alternative. Does olive oil consumption produce obesity? Does oleic acid make the toxicity of linoleic acid worse? What do the study papers really show? Listen to the full podcast as Tucker and Brad try to solve this contentious issue that hovers over not only the future of human nutrition but also how we interpret key food data.
Tucker Goodrich is an advisor to and investor in Zero Acres Farms, which produces a low-linoleic, high-oleic oil. Brad Marshall is the proprietor of Fire in a Bottle products, which markets low-linoleic meat products and supplements to address a high oleic acid intake.
Tucker's blog: http://yelling-stop.blogspot.com
Brad's website: https://fireinabottle.net
Website of Zero Acre Farms: https://www.zeroacre.com
Visit A Neighbor's Choice website at https://aneighborschoice.com
Papers cited in this video:
The Plenish study with fat mice on MUFA: https://link.springer.com/content/pdf/10.1038/s41598-017-12624-9.pdf
Brad used the supplemental data from this paper for liver fat and for plenish vs. soybean oil: https://static-content.springer.com/esm/art%3A10.1038%2Fs41598-017-12624-9/MediaObjects/41598_2017_12624_MOESM1_ESM.pdf
Oleic acid upregulates hepatic lipogenesis (and D6D): https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181393
Rats, lipogenic enzymes and fatty liver: https://www.sciencedirect.com/science/article/abs/pii/S0899900701005135
Pigs and lipogenic enzymes: https://www.karger.com/Article/Abstract/12722
Human risk from D6D and other desaturase enzymes: https://academic.oup.com/ajcn/article/93/1/127/4597607