According to the CDC, 6 in 10 adults in the U.S. have a chronic disease like cancer or diabetes. Meanwhile, the process for discovering new drug treatments is critically expensive and inefficient. About 90% of drug candidates fail to gain FDA approval; the average cost to develop a new drug is over $1 billion; and testing can take over 10 years.
Noam Sol ... Show More
Jan 29
Advice Line with Serial Entrepreneur Mark Cuban
Plus, Mark on his most challenging venture yet: revolutionizing the prescription drug market in America.First we meet Lucy from Washington DC, considering an opportunity to bring her upside-down peanut butter brand into a big box retailer. Then Macy from Utah, wondering if her yo ... Show More
53m 13s
Jan 22
Advice Line with Monica Nassif of Mrs. Meyers
Plus, how candor has been a more effective press strategy than talking points for (the literal) Mrs. Meyers.First we meet Allison in California, seeking marketing ideas for her novel wig designs which aren’t done justice by photos alone. Next, Nick in Idaho wonders whether retail ... Show More
40m 40s
Oct 2022
A New Drug For A Relentless Brain Disease
ALS is a disease that destroys the nerve cells in the brain and spinal cord we need for voluntary movement. There is no cure, but now there is a newly approved medication that may slow down the disease and extend patients' lives. The drug, called Relyvrio, got its start with a co ... Show More
13m 5s
Nov 2022
Battling Pathogens and Building Immunity Begins In Your Gut – Dr. Robynne Chutkan : 998
<p><strong>IN THIS EPISODE OF THE HUMAN UPGRADE</strong>™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn:</p><ul><li>how your microbiome continually ... Show More
1h 17m
Mar 2023
Antibiotics: How to fix a broken market
Antibiotics stopped providing big gains for pharmaceutical companies decades ago, but as bacteria become more resistant to drugs, the world needs new classes of antibiotics to be discovered if we want to prevent the next global health crisis.Dr Tina Joshi, Associate Professor of ... Show More
18m 23s
Feb 2023
Covid Brain Fog, Freemium Failure, Fungal Vaccine
Today you’ll learn about a potential new treatment for those suffering from brain fog after Covid, how freemium models of mental health apps might cause you to be more stressed out, and how developments in creating a vaccine for fungal infections might make them a thing of the pa ... Show More
19m 56s
Sep 2022
Use Your Microbiome for Better Mood, Memory, and Dreams with Dr. Jeffrey Bland
<p>What role does your microbiome take in shaping your moods, memory, and even your dreams?</p> <p>You already know that what you eat matters, especially for your brain matter. The mind-gut connection is so strong, I’ve often referred to it as your second brain. But this intercon ... Show More
20m 40s