Podcast 827: Allergies in Peds

Contributor: Aaron Lessen, MD

Educational Pearls:

• Recent study evaluated if early exposure to an allergen impacted the rate of allergy development later in childhood
• Children were exposed to peanut, milk, wheat, and egg allergens at 3 months of age and then followed for 3 years
• 2.5-3% of children who were not exposed developed allergies to these allergens
• 1% of children exposed to the allergens developed allergies to these allerrgens
• Exposing 63 children to allergens at 3 months would prevent the development of food allergy in one child with no significant adverse events
• Future recommendations will likely be to gradually introduce allergens to children starting around 3 months

References

Skjerven HO, Lie A, Vettukattil R, et al. Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial. Lancet. Jun 25 2022;399(10344):2398-2411. doi:10.1016/s0140-6736(22)00687-0

Summarized by Mark O’Brien, MS4 | Edited by John Spartz, MD, & Erik Verzemnieks, MD

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