logo
episode-header-image
Jun 2021
51m 36s

Talk Evidence - GP data, excess mortalit...

The BMJ
About this episode
In this Talk Evidence, Helen Macdonald, Joe Ross and Duncan Jarvies discuss what's going on in the world of EBM. Firstly, a while ago on the podcast, we concluded that excess mortality would be the best way to measure the impact of the pandemic - and now a new paper looks at different country's excess mortalitites over the past year. We're joined by author Nazrul Islam Physician-Epidemiologist at the University of Oxford (and a research editor for The BMJ) to talk about why comparisons may still not be sensible. Read the full research here - https://www.bmj.com/content/373/bmj.n1137 The Delta variant is dominating headlines, and infections in the UK now - but until recently the Alpha one was ascendent, and new research has helped characterise how the mortality rate of that variant differed from previous viruses. We discuss how that research was done. Read the full research - https://www.bmj.com/content/372/bmj.n579 GP data in the UK - the planned cut-off for granting access to your GP data for researchers has been extended, but there are still a lot of questions remaining. Helen has tried to find out some basic answers, and is still confused. Finally, the FDA has approved a new drug for treatment of dementia - and researchers (and the FDA's own panel of experts) are up in arms. Joe Ross tells us why he thinks the decision was the wrong one, and why patients may be harmed because of it.

https://edition.cnn.com/2021/06/17/opinions/biogen-alzheimers-drug-opinion-ramachandra-ross/index.html

Up next
Jul 1
The power and the pitfalls of early diagnosis
There is a growing market of new diagnostic tests being targeted directly to consumers, often before high-quality evidence about their effectiveness is available. This is causing issues in clinical practice as patients arrive at the NHS’s front door with results that have alarmed ... Show More
40m 52s
Jun 23
Gabapentinoid pain meds linked to self-harm, and getting to the Core of GRADE
Helen MacDonald and Juan Franco are back to examine the newest in evidence based medicine. In this episode: gabapentinoids are medications routinely prescribed for treating epilepsy and nerve pain. But, they come with side effects; among them - dizziness, cognitive impairment, an ... Show More
33m 36s
Apr 17
The evidence on physician associates, and the evidence against back pain injections
Helen MacDonald and Juan Franco are back, magnifying glasses in hand, to take a closer look at what’s happening in evidence based medicine.   In this episode: the NHS increasingly relies on physician associates to plug some of its leaks. But, what do academic studies show about t ... Show More
31m 35s
Recommended Episodes
May 2022
Talk Evidence - evidence in Roe vs Wade, MI treatment variation, and tribal methodologies
Helen Macdonald, The BMJ's research integrity editor is back with another episode, and this week is joined by Joe Ross, professor of medicine and public health at Yale, and US research editor for The BMJ, and Juan Franco, editor in chief of BMJ EBM, and Professor at the Instituto ... Show More
46m 20s
Nov 2022
Talk Evidence - Diabetes data, colonoscopies, and researchers behaving badly
In this month's Talk Evidence, Helen Macdonald, The BMJ's research integrity editor, is joined again by Juan Franco, editor in chief of BMJ EBM, and Joe Ross, US research editor. They're straying beyond the pages of The BMJ, and discussing an NEJM paper about colonoscopy for colo ... Show More
46m 15s
Jun 2021
Talk Evidence - GP data, excess mortality and FDA approval
In this Talk Evidence, Helen Macdonald, Joe Ross and Duncan Jarvies discuss what's going on in the world of EBM. Firstly, a while ago on the podcast, we concluded that excess mortality would be the best way to measure the impact of the pandemic - and now a new paper looks at diff ... Show More
51m 36s
Oct 2022
Talk Evidence - Inquiring about covid, burnout, and marginal data
It's October's Talk Evidence, and that means the autumn is upon us including those autumnal viruses. Here in the UK covid is on the rise, and Joe Ross is looking at some research on how good those elusive lateral flows are at detecting infection among people with symptoms of covi ... Show More
36m 31s
Aug 2023
Aug 11, 2023 This Week in Cardiology Podcast
Observational studies, another defense of digoxin, CTO-PCI, BP measurement, and a possible revolution in cardiovascular protection are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial tra ... Show More
29m 25s
Jul 2022
Talk Evidence - shoulders, knees, and woes
In this episode, Juan Franco, editor in chief of BMJ EBM, and Helen Macdonald, The BMJ's research integrity editor, sit down to discuss what's new in the world of evidence. Firstly, last week they went to the first EBM Live conference for two years - and report back on what happe ... Show More
37m 45s
Jun 2023
Talk Evidence - post pandemic pruning, breast cancer screening, and orphan drugs
In this episode of Talk Evidence,  Helen Macdonald, Joe Ross, and Juan Franco are back to update us on what's happening in the world of medical evidence. Firstly, the news about the end of the covid-19 pandemic was trumpeted, but the changes to research funding have been more qui ... Show More
36m 43s
May 2024
May 10 2024 This Week in Cardiology
Inclisiran, sodium-channel blocker safety, analytic flexibility, the work-up of patients with HF, and BP in older patients are the topics John Mandrola, MD, covers in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or ... Show More
31m 56s
Dec 2023
Dec 15 2023 This Week in Cardiology
FDA approves PFA, breakthrough in PAH, residual leaks after percutaneous LAAO, OAC in low to intermediate risk people are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to ... Show More
29m 5s
Mar 2024
Mar 08 2024 This Week in Cardiology
Plastics and heart disease, MINT trial letters-to-the-editor and Bayes theorem, and Brugada syndrome are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: ... Show More
26m 53s