logo
episode-header-image
Dec 2023
29m 5s

Dec 15 2023 This Week in Cardiology

MEDSCAPE
About this episode

FDA approves PFA, breakthrough in PAH, residual leaks after percutaneous LAAO, OAC in low to intermediate risk people are the topics John Mandrola, MD, discusses in this week’s podcast.

This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. FDA Approves PFA

FDA Approves First Pulsed Field Ablation System for AF https://www.medscape.com/viewarticle/fda-approves-first-pulsed-field-ablation-system-af-2023a1000vit

- PULSED AF https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.064329

- ADVENT Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2307291

- MANIFEST https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.064959

II. Pulmonary HTN

Positive Topline Data for Sotatercept in PAH: STELLAR

https://www.medscape.com/viewarticle/982407

- STELLAR https://www.nejm.org/doi/10.1056/NEJMoa2213558

- Editorial on STELLAR https://www.nejm.org/doi/full/10.1056/NEJMe2300324

III. Peri-Device Leaks

- Greek Meta-analysis https://doi.org/10.1093/eurheartj/ehad828

IV. Intermediate Risk AF – Norwegian Study

- Stroke and bleeding risk in atrial fibrillation with CHA2DS2-VASC risk score of one: the Norwegian AFNOR study AFNOR Study https://doi.org/10.1093/eurheartj/ehad659

You may also like:

Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine

https://www.medscape.com/features/public/machine

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact news@medscape.net

Up next
Yesterday
Oct 10 2025 This Week in Cardiology
GLP-1 use in HFrEF, left atrial posterior wall isolation during AF ablation, peri-device leaks for LAAO, new findings in post-cardiac surgery AF, and imaging before AF ablation are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for health ... Show More
26m 2s
Oct 3
Oct 03 2025 This Week in Cardiology
Two great stories of translation science leading to beneficial drugs in terrible diseases of the heart and the Sisyphean task of predicting the need for pacing after TAVI are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare p ... Show More
26m 50s
Sep 26
Sep 26 2025 This Week in Cardiology
A bold trial in valvular heart disease, a CV prevention trial whose message is humility, VTE dogma challenged, more news on oral GLP-1 agonists, and a few public service announcements are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for ... Show More
22m 50s
Recommended Episodes
Sep 2023
Left-Digit Bias and Other Random Acts of Medicine
A new book reveals how chance can change the course of a person's health, life, and death. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https://www.medscape.com/features/public/machine Eric J. ... Show More
39m 38s
Nov 2023
66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode: ESCMID brain abscess guidelines: https://www.sciencedirect.com/scien ... Show More
34m 48s
Jun 2023
Tragedy, Hope, and a Medical Mystery: 'The Covenant of Water'
Dr Eric Topol and Dr Robert Harrington interview Dr Abraham Verghese about his fiction writing methods and Oprah's enthusiasm for his latest novel. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: ... Show More
43m 8s
Apr 2022
Cure, Prevent, or Manage All Disease: The Chan Zuckerberg Initiative's Bold Plan Is Already Working
Dr Eric Topol sits down with Mark Zuckerberg and Priscilla Chan to talk about the next phase of their ambitious Chan Zuckerberg Initiative. This podcast is intended for US healthcare professionals only. To read a full transcript of this episode or to comment please visit: https:/ ... Show More
36m 32s
Oct 2020
18: Is mixing in lidocaine effective for preventing burning with propofol?
In this episode, we discuss the mechanisms of burning with propofol infusion and explore the evidence behind strategies like mixing lidocaine with propofol. Our guest today is Dr. Stu Forman, Professor of Anesthesiology at Massachusetts General Hospital. He is an investigator on ... Show More
28m 30s
Mar 2024
ECMO for Respiratory Failure
In this episode, Dr. Zanotti is joined by Dr. Craig Rackley to discuss the role of ECMO – extracorporeal membrane oxygenation in supporting patients with acute respiratory failure. Dr. Rackley is a practicing pulmonary critical care physician and an associate professor of Medicin ... Show More
1h 7m
Nov 2023
65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode: UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our- ... Show More
27m 34s
Feb 2024
#750 - Dr Rhonda Patrick - The Most Important Daily Habits For Health & Longevity
Dr Rhonda Patrick is an biomedical scientist, researcher and a podcaster.Determining the best actions to take for enhancing our health and extending our lives has grown more challenging. There are an unlimited number of wellness approaches at our disposal, thankfully Dr Patrick h ... Show More
2h 57m
Feb 2024
Cardiovascular Disease & Brain Aging During Menopause with Rebecca Thurston, PhD (Episode 166)
For years, hot flashes and night sweats (aka vasomotor symptoms) were considered just a “bothersome” part of being a menopausal woman: we were to wear layers, buy a fan, and soldier on. Then researchers started making some troubling connections between vasomotor symptoms and chro ... Show More
55m 51s
Dec 2023
Behind the Knife ABSITE 2024 - Trauma - Part 1
Behind the Knife ABSITE 2024 – Brand new, up-to-date, high yield learning to help you DOMINATE the exam. Don’t forget to check out our NEW ABSITE Podcast Companion Book available on Amazon: https://www.amazon.com/Behind-Knife-ABSITE-Podcast-Companion/dp/B0CLDQWZG3/ref=monarch_sid ... Show More
40m 38s