If you're launching a moonshot, success depends on how you manage the trajectory of risk. When Stéphane Bancel became Moderna's first CEO, the biotech start-up was chasing a way-out idea many experts thought was impossible. Stéphane built a culture of calculated risk-taking to create a platform for extraordinary leaps — one that enabled life-saving mRNA vacc ... Show More
Aug 20
How Barnes & Noble made a comeback, with CEO James Daunt
CEO James Daunt has now rescued two iconic bookstore chains: Barnes & Noble and Waterstones. He joins host Jeff Berman to discuss the turnarounds, plus how bookstores are preparing for an onslaught of AI-written content, his BookTok strategy, and why local control is the key to m ... Show More
32m 54s
Aug 18
What the jobs report isn't telling you about AI & the workforce, with Upwork’s Hayden Brown
Few leaders have a better real-time read on how AI is actually reshaping the workforce than Hayden Brown. As CEO of Upwork, the platform where 18 million freelancers meet the businesses that need them, she sees what the monthly jobs report can't: which skills are surging, which j ... Show More
30m 3s
Sep 2021
The Innovation System Behind Moderna’s Covid-19 Vaccine
Noubar Afeyan, cofounder and chair of Moderna Therapeutics and CEO of Flagship Pioneering, says that the breakthrough innovation behind the company’s Covid-19 vaccine came not as a stroke of luck, but from a repeatable process. He outlines a system called “emergent discovery” tha ... Show More
21m 18s
Apr 2024
301: Biotech mega-rounds, a cancer vaccine setback & CEOs keep their promise
Oruka Therapeutics CEO Lawrence Klein joins us to discuss how his company raised its first round of financing before competing with major players in the inflammation space. We also discuss the latest news in the life sciences, including the end of the Amylyx ALS saga, another use ... Show More
31m 37s
Feb 2021
Responsible Innovation and Venture Capital
Hemant Taneja, a managing director at General Catalyst and the founder of the firm’s Silicon Valley operations, joins Scott to discuss the venture capital space, why he’s bullish on the healthcare sector, and why responsible innovation is more important than ever. Hemant also sha ... Show More
1h 3m
May 2022
38. Pfizer’s CEO on the Big Gamble That Brought Us the COVID Vaccine
Bapu Jena talks with Albert Bourla about his unusual path to the top, developing a life-saving vaccine in record time, and the second-hardest decision he made along the way. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use ... Show More
34m 18s