In the field of bio-tech, it can take 10 years and millions of dollars to see if an experimental idea might turn into a life-saving treatment—if it ever does. Noubar Afeyan fully understood those risks when he co-founded Moderna in 2010. He and his colleagues were looking for a way to deploy the messenger RNA molecule to tackle life-threatening diseases. In ... Show More
Oct 5
10 Years of How I Built This: A Decade of Innovation, Risk and Reinvention
Stories about starting a business are almost always full of drama. They’re about ambition, loss, triumph, catastrophe, resilience. And they’re also full of life lessons – which is why Guy Raz launched How I Built This 10 years ago: He wanted to host a free master class in entrepr ... Show More
1h 10m
Oct 1
Advice Line with Scott Tannen of Boll & Branch and Jamie Siminoff of Ring (2025)
CEO and co-founder of Boll & Branch, Scott Tannen joins Ring founder Jamie Siminoff and Guy on the Advice Line to answer questions from three early-stage entrepreneurs. Plus, Jamie and Guy talk about how creating repeat customers often comes from creating social good. First, we h ... Show More
46m 9s
May 2022
Extraordinary leaps need solid foundations, part 1, w/Moderna CEO Stéphane Bancel
If you're launching a moonshot, success depends on how you manage the trajectory of risk. When Stéphane Bancel became Moderna's first CEO, the biotech start-up was chasing a way-out idea many experts thought was impossible. Stéphane built a culture of calculated risk-taking to cr ... Show More
34m 3s
Jun 2021
Moderna: The Software of Life - [Business Breakdowns, EP. 13]
Today, we will be diving into Moderna. Founded in 2010, Moderna and its innovative RNA platform made headlines after developing one of the first COVID vaccines. We treated this Breakdown slightly different than our other episodes. I’m joined today by two guests. First, I am joine ... Show More
1h 9m
Apr 2021
Vaccine Wars | This is Not a Drill | 1
It’s early January 2020, and a mysterious new virus is overtaking the city of Wuhan, China.At first the outbreak barely makes the news, but as the threat comes into focus, scientists spring into action to make a vaccine. But the outlook’s grim – vaccines take years to create, tes ... Show More
26m 16s
Sep 2021
Meet the scientist couple driving an mRNA vaccine revolution | Uğur Şahin and Özlem Türeci
As COVID-19 spread, BioNTech cofounders Uğur Şahin and Özlem Türeci had one goal: to make a safe, effective vaccine faster than ever before. In this illuminating conversation with head of TED Chris Anderson, the immunologists (and married couple) share the fascinating story of ho ... Show More
21m 20s