logo
episode-header-image
May 2022
35m 25s

A Trip-Switch for Depression?

Bbc Radio 4
About this episode

Could magic mushrooms be the key to a revolution in treating depression? Professor David Nutt, director of the Imperial Centre for Psychedelic Research, thinks so. He tells Vic Gill about recent research suggesting that psilocybin - the psychedelic compound found in magic mushrooms - triggers rewiring of the brain in people with treatment-resistant depression. Vic Gill speaks with trial participant Steve Shorney who was diagnosed with depression 30 years ago.

Nanobodies. That's the name scientists have given to the tiny antibodies found in the blood of camelids like llamas, alpacas and camels. Reporter Samara Linton heads to Berkshire to meet the llamas whose nanobodies were recently found to neutralise the Covid-19 virus. We hear from Professor Gary Stephens, University of Reading, who is responsible for the llamas' safety and well-being, and Professor James Naismith, director of the Rosalind Franklin Institute which is carrying out the pioneering research with engineered nanobodies.

And just as the James Webb Space Telescope is poised to peer deep into the universe, we look at a recent image captured by its great predecessor, Hubble, which has thrown down a telescopic gauntlet. Astronomer Dr Emma Chapman, author of the book “First Light” guides us through these incredible pictures of the furthest, faintest, most ancient of stars yet seen.

Presented by Victoria Gill Reporter: Samara Linton Producer: Alex Mansfield

Up next
Oct 9
Could we have evidence of life on Mars?
News broke this week that rocks picked up by NASA’s Perseverance rover on Mars may have found chemical signatures left by living organisms. With the search for life on the red planet capturing our imaginations for decades, Victoria Gill is joined by science journalist Jonathan Am ... Show More
30m 9s
Oct 2
What does caffeine do to our bodies?
Sweet, caffeinated energy drinks are in the headlines again as the UK Government says it wants to ban under 16s from buying them. Some can contain the equivalent caffeine as 2 to 4 espressos. James Betts, Professor of Metabolic Physiology at the University of Bath, explains the s ... Show More
28m 21s
Sep 25
Does warm weather mean more rats in UK towns and cities?
Summer heatwaves and missed bin collections have created panic in the press that rat numbers in the UK are increasing. We ask Steve Belmain, Professor of Ecology at the Natural Resources Institute at the University of Greenwich for the science. This summer Wales became the first ... Show More
32m 27s
Recommended Episodes
Apr 2022
How ‘magic mushroom’ chemical treats depression
Brain scanning experiments reveal how psilocybin works to relieve severe depression. Psilocybin is the psychedelic substance in 'magic mushrooms'. The psychoactive chemical is currently in clinical trials in the UK and US as a potential treatment for depression and other mental i ... Show More
1h 14m
Aug 2022
Daniel Bergner, "The Mind and the Moon: My Brother's Story, the Science of Our Brains, and the Search for Our Psyches" (Ecco, 2022)
In The Mind and the Moon: My Brother’s Story, the Science of Our Brains, and the Search for Our Psyches (Ecco, 3033), Daniel Bergner examines these and other by describing three riveting case studies in the context of the history of psychiatry and psychopharmacology. Alongside th ... Show More
37m 23s
Jun 2023
Psychedelics
James Gallagher reports on a psychedelic renaissance; a new wave of research testing hallucinogenic drugs like magic mushrooms to treat mental health conditions.There’s genuine excitement and some early encouraging evidence. A manufacturer tells James that in five years’ time, it ... Show More
27m 30s
Nov 2022
Online harassment of Covid scientists
Since the Covid-19 pandemic began, scientists studying the virus have become targets of online harassment, and more recently, death threats. Roland speaks to Dr Angela Rasmussen, virologist at the Vaccine and Infectious Disease Organization at the University of Saskatchewan, abou ... Show More
1h 1m
Dec 2020
Magic Mushrooms: Trip Through the Science
Magic mushrooms have hit the headlines, with people saying that shrooms cured their depression and anxiety. But is this for real? How can taking a trip on psychedelics fix your brain? Today, magic mushrooms ditch their tie dye for a lab coat as we go on a magical journey into the ... Show More
40m 42s
Oct 2022
The Case of The Missing Gorilla
DO WE HAVE YOUR ATTENTION?Good! But how does that work!?Our intrepid science sleuths explore why some things immediately catch your eye - or ear - while others slip by totally unnoticed. Even, on occasion, basketball bouncing gorillas.Professor Polly Dalton, a psychologist who le ... Show More
27m 34s
Nov 2022
Online harassment of Covid scientists
Since the Covid-19 pandemic began, scientists studying the virus have become targets of online harassment, and more recently, death threats. Roland speaks to Dr Angela Rasmussen, virologist at the Vaccine and Infectious Disease Organization at the University of Saskatchewan, abou ... Show More
27m 16s
Feb 2023
The Mind Numbing Medicine
This episode will render you oblivious, conked out and blissfully unaware. It’s about anaesthetics: those potent potions that send you into a deep, deathly sleep. Listener Alicia wants to know how they work, so our sleuths call on the expertise of consultant anaesthetist Dr Fiona ... Show More
43m 44s
Dec 2022
Roland Griffiths & David Yaden || The Scientific Psychedelics Revolution and Embracing Mortality: An Ode to Joy
Today we welcome Roland Griffiths and David Yaden. Dr. Roland Griffiths is a professor of neuroscience, psychiatry, and behavioral science, and director of the Center for Psychedelic and Consciousness Research at Johns Hopkins University School of Medicine. He has authored over 4 ... Show More
1h 21m