logo
episode-header-image
Feb 2023
43m 44s

The Mind Numbing Medicine

Bbc Radio 4
About this episode

This episode will render you oblivious, conked out and blissfully unaware. It’s about anaesthetics: those potent potions that send you into a deep, deathly sleep. Listener Alicia wants to know how they work, so our sleuths call on the expertise of consultant anaesthetist Dr Fiona Donald. Fiona shares her experience from the clinical frontline, and explains what we do and don’t know about how these chemicals work their mind-numbing magic. We hear about ground-breaking research led by Professor Irene Tracey, which reveals how a pattern of slow brain waves can be used to determine the optimum dosage of these dangerous drugs.

And finally, Drs Rutherford and Fry wonder: what does all this tell us about normal consciousness? Professor Anil Seth shares how we can use brain tech to measure different levels of conscious awareness – from sleepy to psychedelic.

Presenters: Hannah Fry and Adam Rutherford Producer: Ilan Goodman

Up next
Jan 2026
Frosty Fractals
One winter morning, listener Jane opened her curtains to find her car roof covered in breathtaking, fern-like frost so intricate it looked like a William Morris print. But how does something as ordinary as ice create patterns so beautifully complex?Hannah and Dara explore this cr ... Show More
29m 10s
Dec 2025
Mining for Gold (GOLD!)
From pharaohs' tombs in Ancient Egypt and medieval currency, to priceless royal jewellery and Spandau Ballet songs - gold has been prized for millennia. But it's only really in the last century or so that we've started uncovering its usefulness in less decorative applications.Tod ... Show More
27m 51s
Dec 2025
Phantom Pain
What exactly is 'phantom pain' and how does it work? Hannah and Dara investigate a medical phenomenon that's been known about for centuries but is often misunderstood; and involves masses of unanswered questions.The condition 'phantom pain' is when someone gets a sensation of pai ... Show More
28m 29s
Recommended Episodes
Apr 2023
The mind-numbing medicine
This episode will render you oblivious, conked out and blissfully unaware. It’s about anaesthetics: those potent potions that send you into a deep, deathly sleep. Listener Alicia wants to know how they work, so our sleuths call on the expertise of consultant anaesthetist Dr Fiona ... Show More
28m 2s
Jul 2023
Focus - When We're Unconscious
What does it mean to be in a coma? How can we tell if someone on life support is actually conscious? And how can scientists use synchronised heart rhythms to predict which comatose patients are likely to wake up? In this focus episode of How We’re Wired, join producer Dr Eva Higg ... Show More
23m 50s
Mar 2015
How Anesthesia Works
<p>The use of general anesthesia is less than 200 years old. Before doctors were able to cause unconsciousness in patients, surgery was brutal for all involved. But despite this advancement in medicine, science still has no idea how it works.</p><p> </p> Learn more about your ad- ... Show More
51m 55s
May 2023
212: The Science of Hypnosis
You're feeling very sleepy... and excited to watch this episode... as we dive into the science of hypnosis!Grab yourself some merch!You can WATCH the podcast over on our YouTube channelHelp keep the show running by supporting us on Patreon!If you'd like to see more of us, follow ... Show More
1h 8m
Apr 2025
Is Hypnotism Real?
Look closer. You are getting sleepier and sleepier. But is it real science? Jorge interviews and gets mesmerized by two hypno-experts.See omnystudio.com/listener for privacy information. 
33m 22s
Sep 2017
The Ostrich Effect
<p>Ignorance is bliss, but knowledge is power...right? In this episode of Hidden Brain, we explore why we sometimes avoid information that's vital to our well-being.</p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> fo ... Show More
25m 5s
Oct 2018
Would You Really Stay Conscious After Being Decapitated?
For everything we know about the human brain, consciousness is still mysterious. Could reports of people remaining conscious after being executed by decapitation be true? Learn what science has to say in this episode of BrainStuff.  Learn more about your ad-choices at https://www ... Show More
6m 55s
Nov 2022
Hypnosis: Does It Really Work?
What is hypnosis? Is it mind control? Are some people just faking? We’re revisiting this episode in which we explore the science of hypnosis and take Science Vs to the edge of consciousness. In the service of journalism, Wendy tries to get hypnotized at a comedy club and in a doc ... Show More
36m 18s
Jun 2013
Sensory Deprivation Chambers
<p>Sensory Deprivation Chambers:Fancy a return to the womb? Ready to shut off the world of senses and dive into the inner you? Well, the sensory deprivation chamber awaits you. In this episode of Stuff to Blow Your Mind, Robert and Julie breakdown the science of the womb-to-tomb ... Show More
32m 22s
Apr 2017
Subconscious
Geoff Lean was in a coma for a month, during this time he could hear and feel everything but it wasn't until he woke up from the coma that he realised he had also unconsciously absorbed visual information through his eyes. Aleks investigates Blindsight, one of the most curious ph ... Show More
27m 59s