Dr Rupert McShane is interviewed about his current research into the antidepressant effects of ketamine infusion
Dec 2023
The Truth About Ketamine: Depression Cure, Health Fad, or Placebo?
One week ago, Matthew Perry’s autopsy report came back, finding that the ‘Friends’ actor died from the acute effects of ketamine overdose. His death has sharpened focus on the popular and controversial drug. Ketamine has been hailed as a miracle cure for depression and anxiety, c ... Show More
43m 52s
May 2025
How Ketamine is Changing Depression Treatment – Dr. John Krystal Explains
Dr. John Krystal, a leading psychiatrist and neuroscientist, explains how ketamine works in the brain, why it’s revolutionizing depression treatment, and what the future holds for psychedelic-assisted therapy. His journey to discovering the revolutionary benefits of Ketamine trea ... Show More
21m 52s
Dec 2024
Your Brain On... Ketamine
For decades, ketamine has mainly been used as an anaesthetic, but in more recent years, it’s gained popularity in mental health treatment. Conversations around the benefits and risks associated with its therapeutic usage ignited towards the end of 2023, when actor Matthew Perry, ... Show More
44m 45s
Jan 2025
Could psychedelics help patients in therapy? | Benjamin Lewis
It's time to make psychiatry more psychedelic, says psychiatrist Benjamin Lewis. Sharing results from his clinical trial on psychedelic-assisted therapy, he highlights how group therapy paired with the safe use of psilocybin, a compound found in magic mushrooms, has the potential ... Show More
32m 3s
Mar 2025
The New Hit Depression Treatment? A Ketamine-Derived Nasal Spray
After it was approved in 2019, Spravato, a depression treatment derived from the club drug ketamine, was looking like a dud. But recently it has taken off, and it surpassed $1 billion in annual sales last year for its maker, Johnson and Johnson.
Further Listening: -A Lawyer Says ... Show More
23m 56s
Jan 2025
Prehabilitation before surgery, alcohol's impact on clinical care, and life after a cardiac arrest
Exercise and a better diet, prior to surgery, can improve outcomes. Daniel McIsaac, a professor of anaesthesiology from the University of Ottowa and lead author of that research, joins us to talk about getting those results into practice.
Julia Sinclair, professor of addiction ps ... Show More
40m 40s
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m