logo
episode-header-image
Sep 2021
36m 4s

Diabetes Core Update SGLT2s and Diabetic...

AMERICAN DIABETES ASSOCIATION
About this episode

In this special episode on SGLT-2 inhibitors and CKD Drs. John Russell and Neil Skolnik discuss the effects of the SGLT-2 inhibitors in decreasing progression of chronic kidney disease.    This special episide is supported by independent educational grant from AstraZeneca.

For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org.

  1. Background, Epidemiology, and Pathophysiology of Diabetic Kidney Disease
  2. ADA Recommendations for Screening and Diagnosis of Diabetic Kidney Disease
  • ADA Recommendations for Treatment of CKD in Persons with Diabetes
  1. Review of the Literature
    1. SGLT-2 inhibitor effects on CV and Kidney Outcomes in Patients with T2DM
    2. Dapagliflozin in Patients with Chronic Kidney Disease
    3. CKD Testing in Patients with T2DM
    4. Second-Line Therapy for T2DM Management: The Treatment/Benefit Paradox of CV and Kidney Comorbidities
    5. eGFR dip After Starting SGLT-2 inhibitors
    6. Dapagliflozin in patients with T2DM and Stages 3b–4 chronic kidney disease

Presented by:

Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health

John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Up next
Oct 8
Special Edition_ MASH Part 1 - Screening
In this special series on Metabolic-Dysfunction Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-associated steatohepatitis (MASH) our host, Dr. Neil Skolnik will discuss Epidemiology, Importance, Screening and treatment of MASH. This special episode is suppor ... Show More
20m 16s
Oct 3
Diabetes Core Update Oct 2025
This issue will review: 1. Once-weekly Ultra-processed Foods and Diet Quality in Association With Long-term Weight Change and Progression to Type 2 Diabetes Among Individuals With a History of Gestational Diabetes Mellitus—A Prospective Study 2. Plant-Based Dietary Patterns Assoc ... Show More
27m 46s
Sep 22
Special Edition - OSA Part 4 – Bringing it All Together
In this special episode on Obstructive Sleep Apnea our host, Dr. Neil Skolnik will discuss treatment of OSA. In Part 1 we discussed an overview of OSA, in Part 2 we discussed making the diagnosis, Part 3 was treatment, and in Part 4 we bring it all together with a case to explore ... Show More
28m 43s
Recommended Episodes
Aug 2022
S1 Episode 1: Chronic Kidney Disease and SGLT2 Inhibitors: Usage, Monitoring, and Possible Side Effects
Drs Sparks and Neuen discuss the proper use of SGLT2 inhibitors to prevent chronic kidney disease, including how to start them and monitor them and their possible side effects. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/vie ... Show More
24m 28s
Jul 2023
S2 Episode 1: What's Your Approach? MRAs and Chronic Kidney Disease
Join experts Drs Matthew Sparks and James Matthew Luther as they discuss how and why they're using mineralocorticoid receptor antagonists to treat patients with diabetic kidney disease in their practice. Relevant disclosures can be found with the episode show notes on Medscape (h ... Show More
29m 53s
Aug 2019
Nephroprotektion durch SGLT-2-Inhibitoren
Revolution zur Behandlung chronischer Nierenerkrankungen? Studientelegramm 73-2019-3/3 Titel der Studie: Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy Autoren: Perkovic et al. Journal: New England Journal of Medicine (NEJM) AMBOSS-Inhalte: Therapie der chron ... Show More
7m 36s
Aug 2021
USPSTF Recommendation: Screening for Prediabetes and Type 2 Diabetes
Interview with Chien-Wen Tseng, MD, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes: US Preventive Services Task Force Recommendation Statement. Related Content: Screening for Gestational Diabetes Screening for Prediabetes and Type 2 Diabetes Updated U ... Show More
16m 25s
Dec 2022
Dec 2, 2022 This Week in Cardiology Podcast
SGLT2 inhibitors, publishing choices, second and third order effects of interventions, decision support, and patient selection for preventive procedures are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. ... Show More
24 m
Apr 2022
#330 Inpatient Diabetes Part 1: Insulin regimens, oral hypoglycemics, corrections scales and more!
Dominate inpatient diabetes! In this part 1 of 2, we discuss how to handle oral hypoglycemics, how to choose an initial insulin regimen, the use of correction scale insulin monotherapy, how to titrate insulin, how to use NPH for steroid-induced hyperglycemia (check out this Twitt ... Show More
1h 20m
Feb 2024
Can type 2 diabetes really be reversed?
Today, we're breaking down a controversial question: can type 2 diabetes be reversed? There are tons of articles out there discussing this hot topic, but we dive into the evidence-based research behind it. Throughout this episode, we dissect the differences between prediabetes an ... Show More
18m 55s
Nov 2023
#279 - AMA #53: Metabolic health & pharmacologic interventions: SGLT-2 inhibitors, metformin, GLP-1 agonists, and the impact of statins
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter explores various pharmacologic tools commonly utilized to improve metabolic health and treat diabetes ... Show More
27m 10s
Jul 2022
Diabetes
Diabetes is an important topic in nursing school, and a common diagnosis that you’ll help treat in your future patients.  In this podcast, I talk about the: Differences between type 1 and type 2 diabetes. Complications such as Neuropathy, Retinopathy, Peripheral Vascular Disease, ... Show More
12m 42s
Jan 2023
179. When the filters start to falter: An approach to CKD management
Send us a textIn this episode, we review the staging, management and treatment options for chronic kidney disease. Though most patients may present asymptomatically at first, we review the symptoms and physical findings to look out for when examining a patient with CKD. Our medic ... Show More
19m 52s