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Dec 2014
1 h

#002 Dr. George Brooks on Lactate Shuttl...

RHONDA PATRICK, PH.D.
About this episode

Dr. George A Brooks

Dr. George A Brooks, an expert in exercise physiology and lactate metabolism. Lactate, a once demonized molecule thought to form lactic acid and become a dead-end toxic metabolite, has been vindicated by the work of Dr. Brooks, his colleagues, and others. 

In this episode, we discuss... 

  • (00:00) Introduction
  • (01:40) Dr. Brooks’ experience as an athlete inspired his research on lactate
  • (06:50) Lactate and its relationship to muscle fatigue is misunderstood
  • (09:10) Adaptations to exercise improve mitochondrial functioning and lactate metabolism
  • (14:14) How to use lactate threshold training to improve performance
  • (23:49) Lactate improves brain health and cognitive function 
  • (26:45) Lactate improves outcomes of traumatic brain injury via metabolism
  • (30:00) Lactate spares glucose, increasing antioxidants such as glutathione
  • (42:50) Early lactate administration following a traumatic brain injury is necessary, but challenging
  • (48:20) Lactate from exercise improves Parkinson's disease 
  • (55:00) Brain metabolism following traumatic brain injury

If you’re interested in learning more, you can read the full show notes here.

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