Sample Size Calculation for a Hypothesis...

<p>Peripheral neuropathy affects approximately 1% of adults worldwide and can be associated with significant disability. Author Michelle Mauermann, MD, of the Mayo Clinic in Minnesota joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss diagnosis and optimal management of p ... Show More

Metabolic dysfunction-associated steatotic liver disease (MASLD), an increasingly prevalent condition among adults worldwide, is associated with liver-related complications, hepatocellular carcinoma, and certain extrahepatic cancers. Author Norbert Stefan, MD, from the University ... Show More

The JAMA Summit on Firearm Violence convened 60 thought leaders from a wide array of disciplines to chart a roadmap that could lead to substantial reductions in firearm harms by 2040. Frederick P. Rivara, MD, MPH, of the University of Washington joins JAMA Editor in Chief Kirsten ... Show More

One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas. 

<p>In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Dr. Michael Sjoding. They discuss his NEJM publication about bias in pulse oximetry measurement. Dr. Sjoding is an Assistant Professor in the Division of Pulmonary and Critical Care at the Uni ... Show More

One of the hottest topics in modern physics is trying to understand the scattering of fundamental particles with neither shape nor size - one step up from nothingness. Amazingly, attempts to understand these simple processes theoretically require state-of-the-art mathematics. The ... Show More

Tomas Kalincik, Head of the Clinical Outcomes Research Unit at the University of Melbourne, and Maria Pia Sormani, Professor of Biostatistics at the University of Genoa, discuss the use of real-world data to compare disease-modifying treatments (DMTs) in multiple sclerosis, inclu ... Show More

<p>Eric Larson and Isabel Vogt have solved the interpolation problem — a centuries-old question about some of the most basic objects in geometry. Some credit goes to the chalkboard in their living room. Read more at QuantaMagazine.org. Music is “Good Times” by Patrick Patrikios.< ... Show More

Kelley Kidwell, PhD, professor of biostatistics, University of Michigan, discusses Sequential, Multiple Assignment, Randomized Trial Designs with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Sequential, Multiple Assignment, Randomized Trial Designs 

A.J. Holmgren, PhD, an assistant professor in the department of medicine at UC San Francisco, discusses EHR quality measurement, quality of care and patient outcomes. This episode is part of the Health IT series by the AMA-MSS Committee on Health Information Technology, hosted by ... Show More

Our guest in this episode is Sebastien Motsch, an assistant professor at Arizona State University, working in the School of Mathematical and Statistical Science. He works on modeling self-organized biological systems to understand how complex patterns emerge. 

The t-test is this week's mini-episode topic. The t-test is a statistical testing procedure used to determine if the mean of two datasets differs by a statistically significant amount. We discuss how a wine manufacturer might apply a t-test to determine if the sweetness, acidity, ... Show More