Sample Size Calculation for a Hypothesis...

POTS is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. Author Satish Raj, MD, MSCI, of University of Calgary Cumming School of Medicine joins JAMA Deputy Editor Kr ... Show More

Naltrexone, acamprosate, disulfiram, and topiramate are effective but underused medications for treatment of alcohol use disorder. Author Stephen Holt, MD, MS, of Yale School of Medicine joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss first-line pharmacotherapy for al ... Show More

Circulating tumor DNA (ctDNA)(liquid biopsies) can help monitor cancer progression, detect residual cancer after treatment, and identify genetic changes within cancer cells that could affect treatment response. Author Ben Ho Park, MD, PhD, of the Vanderbilt-Ingram Cancer Center d ... Show More

One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas. 

Today’s episode of Uncertain is about the ways that studies can leave us overconfident and how “just-so stories” can make us feel overly certain about results that are still a work in progress. And sometimes studies get misleading results because of random error or weird samples ... Show More

<p>Normal Curves is a podcast about sexy science &amp; serious statistics. Ever try to make sense of a scientific study and the numbers behind it? Listen in to a lively conversation between two stats-savvy friends who break it all down with humor and clarity. Professors Regina Nu ... Show More

Medical news can be exciting or controversial. However, the key to any research is its validity through statistical analysis. Professor Chris Schmid, is the Head of Biostatistics at Brown University, and shares his wealth of knowledge how to interpret medical studies.Contact Dr. ... Show More

There are several factors that are important to selecting an appropriate sample size and dealing with small samples. The most important questions are around representativeness - how well does your sample represent the total population and capture all it's variance? Linhda and Kyl ... Show More

<p>There’s a sticky issue scientists have to deal with – science is carried out by humans. We humans have flaws (and how) and they can end up in our work. Fortunately, science is waking up to research bias. In the meantime, here’s what to look out for.</p><p> </p> Learn more abou ... Show More

This week, we're talking about the so-called scientific reproducibility crisis: an alarming sounding study was released earlier this year which concluded that less than one third of breast cancer research papers had reproducible results. So who's to blame? Like this podcast? Plea ... Show More

At a niche engineering conference, a young researcher shares some data that looks like an embarrassing mistake. Little does he know, his simple bar chart is the first pebble in an avalanche exposing a scandal of epic proportions. Producer: Ilan Goodman Sound Designer: Jon Nicholl ... Show More

Candidates mess up calculations for 4 primary reasons: missing units, complicated equations, weak visual layout and poor technique. Notice that we ignore speed and arithmetic. There is a reason for that and it is discussed in the podcast. The most surprising one of the lot is mis ... Show More

<p>Lots of psychology studies fail to produce the same results when they are repeated. How do scientists know what's true?</p><br/> <p>Hosted by Simplecast, an AdsWizz company. See <a href="https://pcm.adswizz.com">pcm.adswizz.com</a> for information about our collection and use ... Show More