571: How low can the dose of ketamine fo...

Show notes at pharmacyjoe.com/episode1054. In this episode, I'll discuss the optimal dosing regimen for meropenem and piperacillin/tazobactam in critically ill patients receiving continuous renal replacement therapy. The post 1054: What is the optimal meropenem and piperacillin/t ... Show More

Show notes at pharmacyjoe.com/episode1053. In this episode, I’ll discuss predicting the chance of successful sedation and the development of hypotension with dexmedetomidine. The post 1053: The Sicker the Patient, the Worse Dexmedetomidine Performs? appeared first on Pharmacy Joe ... Show More

Show notes at pharmacyjoe.com/episode1052. In this episode, I’ll discuss the most effective and safest therapies for nausea/emesis in adult patients presenting to the emergency department (ED). The post 1052: The Best and the Worst Antiemetics in the ED appeared first on Pharmacy ... Show More

Contributor: Travis Barlock MD Educational Pearls: Ketamine is an NMDA receptor antagonist with a wide variety of uses in the emergency department. To dose ketamine remember the numbers 0.3, 1, and 3. Pain dose For acute pain relief administer 0.3 mg/kg of ketamine IV over 10-20 ... Show More

Dr. Mike Dow is healing severe mental disorders with ketamine. The certified psychedelic ketamine-assisted psychotherapist advocates for the drug that is more effective than standard antidepressants. Today, Dr. Dow shares the history of ketamine and how it has been developed to h ... Show More

On this episode I discuss the basics with acetaminophen and which disease states and other medications to look out for when you have patients taking acetaminophen.  Other items discussed on the podcast Mechanism of action Adverse effects Dosing Drug interactions Comparison to NSA ... Show More

Contributor: Don Stader, MD Educational Pearls: Fentanyl’s common administration route through pills has lowered the psychological barrier of using opioid compared to injecting and smoking heroin Fentanyl is showing up in all illicit drugs with documented cases even in marijuana ... Show More

Contributor: Aaron Lessen MD Educational Pearls: Opioid overdoses that are reversed with naloxone (Narcan), a mu-opioid antagonist, can precipitate acute withdrawal in some patients Treatment of opioid use disorder with buprenorphine can also precipitate withdrawal Opioid withdra ... Show More

In this podcast episode I discuss the pharmacology of NSAIDs and the potential collateral damage that can result from these medications.  We’ll cover: Side effects Mechanism of Action Important Drug Interactions Pharmacokinetics between ibuprofen and naproxen Boxed Warnings Hope ... Show More

Contributor: Aaron Lessen, MD Educational Pearls: What is Tranq? Tranq is the street name for xylazine, a sedative drug typically used in veterinary medicine. Xylazine has recently emerged as a recreational drug, often mixed with heroin or fentanyl.  The mechanism of action of xy ... Show More

In this episode on tramadol I cover; Mechanism of action Adverse effects Precautions Drug Interactions Clinical Pearls Enjoy the episode!