About this episode
Feb 2026
The Mariana Trench
58m 4s
Jul 2025
The Evolution of Lungs
48m 24s
Jun 2025
Lise Meitner
57m 22s
May 2019
Episode 5: Solving Structures with X-Rays
1h 7m
Oct 2014
Elspeth Garman on crystallography
27m 23s
Feb 2018
Richard Henderson zooms in on the molecules of life
29m 32s
Oct 2022
The Electron
49m 47s
Jul 2014
The Sun
47m 27s
Aug 2023
Mapping the universe
35m 18s
Aug 2018
Making Natural Products in the Lab
27 m
Mar 2024
Heisenberg's Uncertainty Principle
58m 2s
Nov 2023
The Life Scientific: Paul Murdin
27m 44s
Jan 2024
12 days of Christmas - science version
28m 20s
Melvyn Bragg and his guests discuss the history of crystallography, the study of crystals and their structure. The discovery in the early 20th century that X-rays could be diffracted by a crystal revolutionised our knowledge of materials. This crystal technology has touched most people's lives, thanks to the vital role it plays in diverse scientific disciplines - from physics and chemistry, to molecular biology and mineralogy. To date, 28 Nobel Prizes have been awarded to scientists working with X-ray crystallography, an indication of its crucial importance.
The history of crystallography began with the work of Johannes Kepler in the 17th century, but perhaps the most crucial leap in understanding came with the work of the father-and-son team the Braggs in 1912. They built on the work of the German physicist Max von Laue who had proved that X-rays are a form of light waves and that it was possible to scatter these rays using a crystal. The Braggs undertook seminal experiments which transformed our perception of crystals and their atomic arrangements, and led to some of the most significant scientific findings of the last century - such as revealing the structure of DNA.
With:
Judith Howard
Director of the Biophysical Sciences Institute and Professor of Chemistry at the University of Durham
Chris Hammond
Life Fellow in Material Science at the University of Leeds
Mike Glazer
Emeritus Professor of Physics at the University of Oxford and Visiting Professor of Physics at the University of Warwick
Producer: Natalia Fernandez.
Misha Glenny and guests discuss one of the wonders of the natural world. In 1875 in the western Pacific, the crew of HMS Challenger discovered the Mariana Trench which turned out to be deeper than Everest is high, by two kilometres. Trenches like Mariana form when one tectonic pl ... Show More
Melvyn Bragg and guests discuss the evolution of lungs and of the first breaths, which can be traced back 400 million years to when animal life spread from rock pools and swamps onto land, as some fish found an evolutionary advantage in getting their oxygen from air rather than w ... Show More
Melvyn Bragg and guests discuss the decisive role of one of the great 20th Century physicists in solving the question of nuclear fission. It is said that Meitner (1878-1968) made this breakthrough over Christmas 1938 while she was sitting on a log in Sweden during a snowy walk wi ... Show More
In this episode we cover the history and development of crystallography, the study of the structures that make up the materials around us. The history of this field is filled with accidental discoveries, ingenious inventions, and drama between those who study it. One of the most ... Show More
Jim al-Khalili talks to Professor Elspeth Garman about a technique that's led to 28 Nobel Prizes in the last century.X- ray crystallography, now celebrating its 100th anniversary, is used to study the internal structure of matter. It may sound rather arcane but it's the reason we ... Show More
What once took decades, now takes days, thanks to an astonishingly powerful new technique invented by Richard Henderson, winner of the 2017 Nobel Prize for Chemistry. Richard grew up in a remote village in the Scottish borders exploring the countryside and reading the weekly bund ... Show More
Melvyn Bragg and guests discuss an atomic particle that's become inseparable from modernity. JJ Thomson discovered the electron 125 years ago, so revealing that atoms, supposedly the smallest things, were made of even smaller things. He pictured them inside an atomic ball like a ... Show More
Melvyn Bragg and his guests discuss the Sun. The object that gives the Earth its light and heat is a massive ball of gas and plasma 93 million miles away. Thanks to the nuclear fusion reactions taking place at its core, the Sun has been shining for four and a half billion years. ... Show More
A rocket launch, super-massive black holes and ghost particles! This past week’s scientific findings are testament to how hard-at-work cosmologists and physicists have been seeking out the fundamental building blocks of our universe and the rules that govern it. Professor of Cosm ... Show More
Philip Ball tells the science story of German chemist Friedrich Wöhler’s creation of urea, an organic substance previously thought only to be produced by living creatures. Yet in 1828 Wöhler created urea from decidedly non-living substances. It was exciting because the accidental ... Show More
Melvyn Bragg and guests discuss the German physicist who, at the age of 23 and while still a student, effectively created quantum mechanics for which he later won the Nobel Prize. Werner Heisenberg made this breakthrough in a paper in 1925 when, rather than starting with an idea ... Show More
Astronomer Paul Murdin believes a good imagination is vital for scientists, since they're so often dealing with subjects outside the visible realm.Indeed, over a long and successful career his imagination has taken him on a journey through space, discovering various new and unusu ... Show More
Marnie Chesterton & Victoria Gill embark on a science-themed version of the classic Christmas song ‘The 12 Days of Christmas’ in this festive edition of BBC Inside Science. Twelve of the biggest moments of the year in science include discussion about a very special treefrog disco ... Show More