433. How Are Psychedelics and Other Part...

A ruthless (and ruthlessly efficient) industry is using digital tools to supercharge one of the world’s oldest behaviors. We look at how the industry works, and ask the scam-fighters what they’re doing about it. SOURCES: Kati Daffan, former assistant director at the Federal Trade ... Show More

Economists don’t usually talk about “culture.” But Joel Mokyr argues that it’s the engine of innovation — and the Nobel Prize committee agreed. Stephen Dubner sits down for a thousand-year conversation (including advice!) with the new Nobel laureate. SOURCES: Joel Mokyr, economic ... Show More

Just beneath the surface of the global economy, there is a hidden layer of dealmakers for whom war, chaos, and sanctions can be a great business opportunity. In this updated episode from 2025, journalists Javier Blas and Jack Farchy help us shine a light on the shadowy realm of c ... Show More

Could psychedelics help us heal from trauma and mental illnesses? Researcher Rick Doblin has spent the past three decades investigating this question, and the results are promising. In this fascinating dive into the science of psychedelics, he explains how drugs like LSD, psilocy ... Show More

<p>In this episode of the Drug Science podcast, Professor Nutt is joined by an old friend who he has known for 35 years. Professor Roland Griffiths is a researcher who has examined a wide range of psychotropic substances through the years. He has studied, the abuse potential of a ... Show More

Dr. Mike Dow is healing severe mental disorders with ketamine. The certified psychedelic ketamine-assisted psychotherapist advocates for the drug that is more effective than standard antidepressants. Today, Dr. Dow shares the history of ketamine and how it has been developed to h ... Show More

In this episode, my guest is Nolan Williams, M.D., a triple board-certified psychiatrist, neurologist and professor of psychiatry and behavioral sciences at Stanford School of Medicine. He is also the Director of the Stanford Brain Stimulation Lab. We discuss clinical application ... Show More

In this episode, I discuss what psilocybin is (chemically) and how it works at the cellular and neural circuit level to trigger neuroplasticity, which is our brain’s ability to rewire itself in ways that lead to long-lasting shifts in our emotional, cognitive and behavioral patte ... Show More

<p>Sam Harris speaks with Roland Griffiths about the current state of research on psychedelics. They discuss the historical prohibition against their use; the clinical and scientific promise of psilocybin, mescaline, LSD, DMT, MDMA, and other compounds; the risks associated with ... Show More