Special Bonus Edition

What is light? How has it shaped our understanding of the universe, our biology, and even our culture? In this illuminating episode Brian Cox and Robin Ince shine a spotlight on the fascinating science and history of light. From sun and circadian rhythms to the dazzling complexit ... Show More

What really separates a moth from a butterfly? Is it just a matter of day and night, or is there more to this fluttering feud than meets the eye? Professor Brian Cox and Robin Ince flap into the fabulous world of Lepidoptera with Professor Jane Hill, Professor Chris Jiggins, and ... Show More

Brian Cox and Robin Ince dig deep into the strata of an imagined human history to unearth the curious concept of technofossils. Joined by paleobiologist Sarah Gabbott, material scientist Mark Miodownik and comedian and tech enthusiast Aurie Styla the panel unearth how the everyda ... Show More

Andy revisits some of his favorite moments on the podcast to celebrate the 100th episode. This week's episode features Maria Bamford, Will Arnett, Deon Cole, Zach Galifianakis, Nicole Byer, and Scott Thompson. 

Rory Scovel is back in the garage, fresh off premiering a new standup special on Max that Marc found extremely funny. Now at a point in his life where his smack in the middle between feeling young and feeling old, Rory talks with Marc veteran comic to veteran comic about their ph ... Show More

Our friend Brian Reich, the legendary Late Night with Conan O’Brien writer responsible for characters like the Masturbating Bear and Pimpbot 5000, passed away on September 12, 2022. We were lucky enough to have him on the show back in November 2021, where he told one of our favor ... Show More

Hey Three Questions listeners, today we’re giving you a taste of a very special episode of Parks and Recollection featuring Chris Pratt! On this episode Chris opens up about his audition for Parks and Rec, working with Mouse Rat song writer Mark Rivers, adapting the character of ... Show More

Drew Michael wants his comedy to feel different. He wants the audience to have a unique experience. This mindset actually reminds Marc of his own style of comedy, as well as a few other iconoclastic stand-ups who used their time on stage to get laughs but also get to the bottom o ... Show More

On today's episode we are jam packed with the entire crew talking Black Holes with physicist Brian Cox (2:02:40), an expert in the field. This is a MUST listen episode. The longest in Macrodosing history. A lot of laughs and great content. As always, we take your voicemails and c ... Show More

“Both he and I are disappointed in the human experiment.” Brian Cox talks about how he relates to his HBO “Succession” character, Logan Roy, but explains why he chooses to be optimistic about society’s ability to do better. Then "Succession" star,  Alan Ruck, discusses the show's ... Show More

This week, host Jesse David Fox previews his new Patreon podcast, The Specials. Along with his co-host, Dave Schilling, and producer, Jessamine Molli, each episode they watch a noteworthy stand-up special from the history of comedy and have as much fun as possible analyzing it as ... Show More