Orphan Drugs

One study from 2018 found that Major League Baseball umpires blow about 14 calls every game. That’s 34,000 bad calls every year. And it makes a difference. A blown strike call can decide a win or a loss, a championship or six months at home, wondering what could have been. And wh ... Show More

A missing car reveals the confusing rules, murky fees, and private actors behind modern towing. What infrastructure mystery keeps you up at night? Submit your Service Request by recording a voice memo with your question and emailing it to servicerequest@99pi.org. Service Request ... Show More

In a place where losing power can turn deadly, keeping the lights on is a high-stakes balancing act. What infrastructure mystery keeps you up at night? Submit your Service Request by recording a voice memo with your question and emailing it to servicerequest@99pi.org. Service Req ... Show More

Melvyn Bragg and guests discuss the history of drugs. Throughout history people have taken them to alter their perceptions and change their moods. The attractions lie in the promise of instant pleasure and the possibility of heightened perceptions. Nietzsche said that no art coul ... Show More

If you had a rare disease and the only drug that could help you suddenly shot up in price how would you feel? What if your health service or insurer decided it was too expensive and they wouldn’t fund it any more? This is the problem facing some patients in the Netherlands.In ord ... Show More

On this week's episode of Networth and Chill, I'm joined by author and CEO of Rhoshan Pharmaceuticals, Hitha Palepu to talk drug prices and the pharmaceutical industry. Drug prices are a hot topic these days, and it seems like the cost of life saving medications like insulin and ... Show More

<p>Drug policy feels very unsettled right now. The war on drugs was a failure. But so far, the war on the war on drugs hasn’t entirely been a success, either.</p><p>Take Oregon. In 2020, it became the first state in the nation to decriminalize hard drugs. It was a paradigm shift ... Show More

The first 'war on drugs' was launched by US President Richard Nixon in 1971. He described drug abuse as a 'national emergency' and asked Congress for nearly four hundred million dollars to tackle the problem. Claire Bowes spoke to one of Nixon's policy advisors, Jeffrey Donfeld, ... Show More

In the 1980s and 90s, pharmaceutical companies began to market opioid painkillers aggressively, while actively downplaying their addictive potential. The number of prescriptions skyrocketed, and so did cases of addiction, beginning a crisis that continues today. What makes opioid ... Show More

Mark Parrino has been involved with the delivery of health care and treatment for opioid use disorder (OUD) since 1974. As the president of the American Association for the Treatment of Opioid Dependence, Inc. (AATOD), he works with treatment providers across the country to devel ... Show More

The buzz: “Although counterfeit drug production was originally concerned with lifestyle medications treating non-life threatening conditions, the industry has expanded to produce nearly every type of medicine” (cnbc.com/id/44759526). The World Health Organization (WHO) estimates ... Show More