Joel Predd, Ben Boudreaux, and Matt Chessen of RAND's Center for the Geopolitics of AGI join Nathan to discuss their framework for maintaining freedom of action on the path to superintelligence. Analyzing seven strategic archetypes—including dominance, deterrence, co-development, and moratoriums—they argue that deep technological and geopolitical uncertainty ... Show More
Yesterday
AI:AM: Carbon in the Arena, Mistral's Le Chonk, the Agent-Run Economy, Ferroelectric RAM + New Hacks
Nathan Labenz and Prakash Narayanan examine whether prevailing AI assumptions survive real-world data across conversations with Anastasios Angelopoulos of Arena, Debo Olaosebikan of Kepler Computing, Samvit Ramadurgam of Union, Michael Freeman of ServiceNow, and Sagar Vaze of Mis ... Show More
1h 27m
Oct 24
AI:AM Highlights: Clean Neurons, Black October, the GPU Credit Crunch, and Buying the Supply Chain
Hosts Nathan Labenz and Prakash Narayanan examine whether capital, physical infrastructure, or regulation will set the pace of artificial intelligence. Zvi Mowshowitz evaluates aggressive recursive self-improvement timelines pointing toward 2027, the oversold claims surrounding c ... Show More
1h 29m
Oct 20
A World Model of Life: Biohub's Alex Rives on Virtual Cells, Measurement, & the $1.8B Data Push
Alex Rives, Head of Science at Biohub and former lead of the ESM protein language model project, joins Nathan to discuss Biohub's mission to construct a predictive world model of life. Supported by an expanded $1.8 billion Virtual Biology Initiative alongside partners including t ... Show More
1h 5m
Mar 2023
AI and Coding with ChatGPT
In this episode of Syntax, Wes and Scott talk about the current landscape of AI, how AI is trained, is AI going to take your job, who’s going to train AI, and adding AI to your applications.
Sentry - Sponsor If you want to know what’s happening with your code, track errors and m ... Show More
1h 6m
Feb 2025
Industry Roundup #3: The Rise of Reasoning LLMs, OpenAI Operator, Project Stargate, and Gemini’s Struggle for Recognition
Welcome to DataFramed Industry Roundups! In this series of episodes, Adel & Richie sit down to discuss the latest and greatest in data & AI. In this episode, we discuss the rise of reasoning LLMs like DeepSeek R1 and the competition shaping the AI space, OpenAI’s Operator and the ... Show More
29m 46s
Apr 2023
E124: AutoGPT's massive potential and risk, AI regulation, Bob Lee/SF update
(0:00) Bestie intros! (1:49) Understanding AutoGPTs (23:57) Generative AI's rapid impact on art, images, video, and eventually Hollywood (37:38) How to regulate AI? (1:12:35) Bob Lee update, recent SF chaos Follow the besties: https://twitter.com/chamath https://linktr.ee/calacan ... Show More
1h 33m
Sep 2025
Inside OpenAI Enterprise: Forward Deployed Engineering, GPT-5, and More | BG2 Guest Interview
Open Source bi-weekly convo w/ Bill Gurley and Brad Gerstner on all things tech, markets, investing & capitalism. This week, guest host Altimeter’s Apoorv Agrawal explores how OpenAI is reshaping enterprise with Sherwin Wu, Head of Engineering OpenAI Platform, and Olivier Godemen ... Show More
1h 8m