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Umbrella: Cardioprotection During Treatm...

AMERICAN COLLEGE OF CARDIOLOGY
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Aug 18
No Murmur But Much Fervor: Nonobstructive HCM
Nonobstructive hypertrophic cardiomyopathy (HCM) represents one of the greatest areas of unmet need in HCM management. A key question is identifying the primary driver of symptoms in these patients, as many experience significant functional limitations despite the absence of left ... Show More
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Aug 11
Evolocumab In Patients Without Significant Atherosclerosis: Results From VESALIUS-CV
The VESALIUS-CV trial demonstrated that the PCSK9 inhibitor evolocumab significantly reduced the risk of a first major cardiovascular event in patients with diabetes who had no known significant atherosclerosis. These findings challenge current clinical practice, where PCSK9 inhi ... Show More
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Aug 4
Why Can't We Prove Revascularization Is Better Than Medical Therapy for SIHD?
Randomized trials in stable ischemic heart disease (SIHD) show revascularization does not reduce death or myocardial infarction versus guideline-directed medical therapy, with benefit limited to symptom relief. This likely reflects lesion–ischemia mismatch, unclear ischemia origi ... Show More
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