In this week's investigation Hot On The Case covers one of the most confusing missing persons cases of all time. Brian Shaffer was a medical student at Ohio State who walked into a crowded college bar, and never walked back out of it. He can be seen on CCTV footage arriving with friends, talking to people outside, and having a seemingly normal night. However, when his friends reappear within sight of the security camera as they leave, Brian is nowhere to be seen. He vanished and has remained that way for over 20 years. The bizarre nature of his disappearance has led to tons of online speculation and multiple theories all trying to answer one question.. What happened to Brian Shaffer?