Chemical cardioversion in the ED, HF monitoring, weight loss in AF, and surgical LAA excision are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Chemical Cardioversion of AF in the ED: The FLECA-ED Trial
- FLECA-ED Rationale paper https://pmc.ncbi.nlm.nih.gov/articles/PMC10299428/
- FLECA-ED ESC Slides https://esc365.escardio.org/presentation/321209
- Review on Flecainide Use Despite CAST https://doi.org/10.1016/j.hrthm.2025.08.034
- RACE 7 ACWAS Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1900353
II Heart Failure Monitoring – The ALLEVIATE-HF Trial
- ALLEVIATE-HF Trial https://doi.org/10.1016/j.jacc.2026.03.075
- CHAMPION Trial https://doi.org/10.1016/S0140-6736(11)60101-3
- GUIDE HF Trial https://doi.org/10.1016/S0140-6736(21)01754-2
- ALLEVIATE-HF Editorial: Alerts Are Not Treatment https://doi.org/10.1016/j.jacc.2026.04.014
- Steve Stiles Medscape report on CHAMPION https://www.medscape.com/viewarticle/755189
III A Negative Weight Loss Study in AF
- LOSE-AF Trial https://jamanetwork.com/journals/jama/fullarticle/2849335
IV Surgical LAA Excision
- OPINION Trial https://doi.org/10.1093/eurheartj/ehaf674
- LAAOS 3 trial https://www.nejm.org/doi/full/10.1056/NEJMoa2101897
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