Hosted by Dr. Lauren Kim, this episode explores the most downloaded Radiology article of 2025 with guests Dr. Carolyn Wang, Dr. Allison Ramsey, and Dr. David Lang, focusing on updated consensus guidance for managing hypersensitivity reactions to iodinated contrast media. The discussion highlights major changes in clinical practice, including more selective use of corticosteroid premedication and switching contrast agents when feasible to reduce the risk of recurrent reactions and standardize patient care.