Josh Weiner left Meta to return to CVS Health with two painful realizations: consumers don't manage their health—they expect it, and the healthcare market fundamentally violates every principle of economics. In this conversation with a16z's Julie Yoo, the CVS Senior VP explains why 50% of Americans can't afford a healthcare emergency, how CVS is becoming a p ... Show More
Nov 17
How to Build This Generation's Big Pharma Company
<p>Drug discovery has doubled the flow of candidates, but approvals remain roughly flat. The constraint is development, not discovery. </p><p>In this episode, a16z General Partner, Jorge Conde talks with Formation Bio cofounder and CEO Ben Liu about building a modern pharma compa ... Show More
41m 4s
Nov 7
Dyno Therapeutics: Empowering Patients with Genetic Agency
<p>For the first time in human history, we can diagnose thousands of genetic diseases—often for under $1,000—but we still can't treat most of them. The problem isn't understanding what's broken; it's delivering the fix to the right cells.</p><p>Eric Kelsic, CEO of Dyno Therapeuti ... Show More
47m 28s
Sep 29
Value-Based Oncology at Scale: Inside Thyme Care
<p>Cancer care in the U.S. costs over $250 billion each year, and nearly 2 million Americans receive a new diagnosis annually, yet too often the journey begins with silence: no call, no plan, no guide.</p><p>In this episode, a16z’s Vineeta Agarwala and Jay Rughani talk with Thyme ... Show More
41m 16s
Feb 2024
Biotech Special: a16z and the Biotech Revolution with Vijay Pande
There is a revolution unfolding in biotech. The confluence of new biological methods like CRISPR, virtually unlimited computational capacity, and machine learning has fundamentally transformed our ability to engineer biology for wide-ranging applications.
Andreessen Horowitz, or ... Show More
57m 1s
Jul 2025
Can AI Accelerate Science? Dr. Andy Beam on AI’s Next Frontier
<p><a href='https://mcdn.podbean.com/mf/web/w5aftmmy3fux99mq/Episode_32_Beam_bio.pdf'>Dr. Andy Beam</a> has trained models, mentored scientists, and used data to quantify the value of treatments. In this episode of NEJM AI Grand Rounds, Raj Manrai turns the table on his co-host, ... Show More
1h 7m
Aug 2024
Reinventing AI Agents with Imbue CEO Kanjun Qiu
In this episode of Gradient Dissent, Kanjun Qiu, CEO and Co-founder of Imbue, joins host Lukas Biewald to discuss how AI agents are transforming code generation and software development. Discover the potential impact and challenges of creating autonomous AI systems that can write ... Show More
48m 37s
Sep 2024
The Road to Autonomous Intelligence with Andrej Karpathy
Andrej Karpathy joins Sarah and Elad in this week of No Priors. Andrej, who was a founding team member of OpenAI and former Senior Director of AI at Tesla, needs no introduction. In this episode, Andrej discusses the evolution of self-driving cars, comparing Tesla and Waymo’s app ... Show More
44m 16s