Breaking news: Jon Krohn welcomes Adrian Kosowski to the show to talk about the groundbreaking research happening at Pathway. Adrian and his team demonstrate how they have brought attention in AI closer to the way the brain functions, creating, in essence, a “massively parallel system of [artificial] neurons” that communicate with one another and exhibit pro ... Show More
Sep 1
1023: Agentic AI Skills That Matter Now, with Aishwarya Srinivasan
In Episode #1023, Aishwarya Srinivasan (Co-Founder of The Gen Academy) joins Jon Krohn to work out where a competitive moat comes from once anything you can build in ten minutes, somebody else can build in ten minutes too. Ash came to teaching through Illuminate AI, the mentorshi ... Show More
1h 18m
Aug 28
1022: CLAUDE.md, AGENTS.md, Skills, Hooks and Subagents: A Field Guide to Steering AI Agents
In Episode #1022, Jon Krohn tackles the art of steering AI agents, deciding where your instructions should live so they get followed reliably without bloating every request. A sequel to Episode #1020 (where model size and effort set an agent’s horsepower), this one is about direc ... Show More
17m 31s
Aug 25
1021: How dbt Won Analytics Engineering, with dbt Lab’s CEO Tristan Handy
In Episode #1021, Tristan Handy (Founder and CEO of dbt Labs) joins Jon Krohn to explain how a study of about a hundred companies in 2016 became analytics engineering, and then became a tool that over a hundred thousand data teams rely on. Tristan coined the term, chose SQL when ... Show More
51m 55s
Feb 2024
When brains and computers meet
Are cyborgs now reality? Elon Musk certainly thinks so. His company, Neuralink, has successfully implanted one of its wireless brain chips in a human. Although billed as a breakthrough, they’re not the first to do it. In fact, similar devices have already been implanted, all with ... Show More
27m 12s
Jun 2024
Synthetic Biological Intelligence with Brett Kagan
<p>Can you make a computer chip out of neurons? Neil deGrasse Tyson, Chuck Nice, & Gary O’Reilly explore organoid intelligence, teaching neurons to play Pong, and how biology can enhance technology with neuroscientist and Chief Scientific Officer at Cortical Labs, Brett Kagan.</p ... Show More
50m 5s
Oct 2025
How CytoReason is Bridging the Data Insight Gap to Accelerate Healthcare Breakthroughs - Ep. 276
Shai Shen-Orr, co-founder and chief scientist at CytoReason and professor at the Technion, talks about the next frontier in healthcare: disease modeling. Shai shares how CytoReason bridges the gap between exploding biological data and actionable insight, powering smarter, faster ... Show More
35m 12s
Feb 2023
Terry Sejnowski: NeurIPS and the Future of AI
<p>In this episode, <a href= "https://twitter.com/sejnowski?lang=en">Terry Sejnowski</a>, an AI pioneer, chairman of the NeurIPS Foundation, and co-creator of Boltzmann Machines, delves into the latest developments in deep learning and their potential impact on our understanding ... Show More
37m 5s