episode-header-image

Jul 2025

5m 8s

Methylprednisolone vs. Hydrocortisone: W...

Eddy Joe Gutierrez, MD

About this episode

Up next

Albumin in Critically Ill Patients: Evidence, Indications, and the 5% vs 25% Debate

Albumin is one of those topics where everyone has an opinion, but very few people actually look at the cost-benefit data. In this lecture, I’m breaking down why the 5% albumin you’re hanging might be a waste of money, and where the 25% concentration actually moves the needle in s ... Show More

Peripheral Vasopressors, Practically Safe: What a 250-Patient Prospective Cohort Means for Your Unit

A new prospective multicenter cohort of 250 patients with shock examines the safety and outcomes of peripheral vasopressor administration. Extravasation events were rare and clustered only after several days of infusion, while norepinephrine use and simple physiologic markers cor ... Show More

CCBs and Oxygenation: Why the Sat Falls After the Drip

Intravenous dihydropyridine calcium channel blockers can quietly worsen oxygenation by blunting hypoxic pulmonary vasoconstriction. In this episode, we break down the bedside mechanism, which agents are implicated, who’s at highest risk (post-op atelectasis, obesity, pneumonia, f ... Show More

Recommended Episodes

Journal Jam 17 – Steroids for CAP and COVID Pneumonia

What are the indications for steroids in patients with pneumonia besides those with concurrent COPD exacerbations, ARDS or adrenal shock? What is the evidence for benefit for steroids in CAP, the flu and COVID pneumonia? And if there is benefit, do those benefits outweigh the pot ... Show More

#141 Do Steroids Have a Role in Community-Acquired Pneumonia? Beyond Journal Club on the CAPE COD Trial

In community-acquired pneumonia, can steroids improve mortality? Past studies of steroids in CAP have been conflicting, with some showing a mortality benefit and others showing no difference. How does the CAPE COD trial change how we think about patients hospitalized with severe ... Show More

Corticosteroids in the Critically Ill

Corticosteroids in the Critically Ill Special Guest: Andrea Nei, PharmD, BCPS, BCCCP, FCCM @Dre_pharmd 04:40 – Guideline introduction/background 08:35 – Scope/authorship 13:35 – PICO questions/recommendations 14:22 – Sepsis 17:20 – CAP 19:10 – ARDS 21:55 – Research priorities/Tak ... Show More

#16 Steroids in COPD: Mind the Gap Segment

Let’s take your breath away… with a review on steroids in treating COPD exacerbations!Time StampsHow does GOLD (Global Initiative for Chronic Obstructive Lung Disease) define a COPD exacerbation? (2:44)What outcomes do steroids actually improve in treating a COPD exacerbation? (5 ... Show More

Podcast 298: COPD exacerbations — 7 days of antibiotics versus 2

<p>A VIDEO RECORDING OF THIS INTERVIEW IS <a href='https://cdn.jwplayer.com/players/cn8xfSaw-rmTFgmxB.html'>AVAILABLE AT THIS LINK</a>.</p> <p>In treating most exacerbations of chronic obstructive pulmonary disease (COPD) the usual regimen consists of prednisone plus 5- to 7-day ... Show More

Episode 159.0 – Acute Decompensated Heart Failure

In this episode, we discuss acute decompensated heart failure and how to best manage these dyspneic patients in the ED. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Podcast_ADHF.mp3 Download Leave a Comment Tags: Cardiology, Respiratory Show Notes Features that inc ... Show More

19: Is hydrocortisone, ascorbic acid (Vitamin C), and thiamine therapy effective for treatment of sepsis?

<p class="p1"><span class="s1">In this episode, we discuss the role of hydrocortisone, ascorbic acid (Vitamin C) and thiamine (HAT therapy) in the treatment of patients with septic shock. We discuss biological plausibility and comprehensively review the latest evidence.</span></p ... Show More

<p>In this episode I cover pneumonia.<br/><br/>If you want to follow along with written notes on irritable bowel syndrome go to <a href='https://zerotofinals.com/pneumonia'>https://zerotofinals.com/pneumonia</a> or find the respiratory section in the Zero to Finals medicine book. ... Show More

Asthma Management: Less is More?

Interesting study today that looks at High dose ICS inhalers possibly have worse outcomes in patients than medium dose ICS inhalers, leading to more exacerbations and need for antibiotics. Plausible? Let's discuss!

Episode 37 - Basic Mechanical Ventilation III: The Role of PEEP & LVRs

What are the determinants of mean airway pressure? Is too much PEEP ever a bad thing? In this episode, we review determinants of oxygenation in mechanically ventilated patients and discuss the benefits and risks of high versus low PEEP strategies, as well as the utility of lung v ... Show More