logo
episode-header-image
May 2025
21m 31s

Diagnosis of Alzheimer Disease Using Pla...

AMERICAN ACADEMY OF NEUROLOGY
About this episode

Dr. Greg Cooper talks with Dr. Joseph Therriault about the use of plasma biomarkers in diagnosing Alzheimer disease, emphasizing the importance of interpreting these biomarkers within the clinical context of the patient. 

Read the related article in Nature.

Disclosures can be found at Neurology.org

Up next
Jul 6
Navigating the Transition From Pediatric to Adult Epilepsy Care
Dr. Dara Albert talks with Dr. Scott Perry about improving the transition from pediatric to adult epilepsy care. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurology.org. 
22m 2s
Jul 2
Communication About Uncertainty During PD Diagnostic Consultations
Dr. Greg Cooper talks with Dr. Elisabeth Kurpershoek about how clinicians communicate uncertainty during Parkinson disease diagnosis and how this impacts patient trust and understanding. Read the related article in Neurology® Clinical Practice. Disclosures can be found at Neurolo ... Show More
16m 19s
Jul 1
July 2026 Recall: Updates in Epilepsy
The July 2026 Recall features four previously posted episodes related to updates in epilepsy. The episode opens with Dr. Rosemary Dray-Spira discussing trends in prenatal exposure to antiseizure medications over the past decade. The episode continues with Dr. Page Pennell discuss ... Show More
1h 8m
Recommended Episodes
Oct 2024
Newly FDA Approved Alzheimer’s Biomarkers Testing: How to Implement Such Tests in Core Laboratory?
<p>The diagnostic paradigm for Alzheimer&apos;s disease (AD) has rapidly shifted in the last five years as fluid-based biomarker testing has emerged as a reliable, accurate, and accessible means to detect amyloid pathology when evaluating a patient for cognitive decline. This pod ... Show More
35m 34s
Oct 2023
Blood Test for Alzheimer Disease
Dr. Rae Bacharach discusses the Neurology Today article, "Individuals Can Now Request a Blood Test for Alzheimer disease - Why Some Dementia Experts Are Wary". Show references: https://journals.lww.com/neurotodayonline/fulltext/2023/10190/individuals_can_now_request_a_blood_test_ ... Show More
2m 37s
May 2015
Biomarkers: Detecting Alzheimer's Early Enough to Treat it.
What are Biomarkers? And why are they useful in Alzheimer's Disease Research. 
21m 55s
Jan 2022
Alzheimer Disease: Diffusion Tensor MRI and amyloid PET
Dr. Manisha Bahl interviews Dr. Jeffrey Prescott. Diffuse Tensor MRI Structural Connectivity and PET Amyloid Burden in Preclinical Autosomal Dominant Alzheimer Disease: The DIAN Cohort. Prescott et al. Radiology 2022; 302:143–150.  
11m 41s
May 2022
Cortex Anatomy and Alzheimer's Disease
There are 6 million Americans living with Alzheimer's Disease. This program explains the latest understanding of the anatomy and functions of the brain and how it relates to neurological diseases. Dr. Gil Rabinovici is at the forefront of novel diagnostic testing to detect Alzhei ... Show More
1h 24m
Mar 2024
Cutaneous Phosphorylated Alpha-Synuclein Deposition in Dementia
Dr. Jason Crowell talks with Dr. Christopher Gibbons to discuss his paper "Cutaneous Phosphorylated Alpha-Synuclein Deposition in Dementia with Lewy Bodies and Mild Cognitive Impairment."   Show reference:  https://index.mirasmart.com/AAN2024/SearchResults.php?Program_Number=PL4. ... Show More
4m 49s
Dec 2023
Dementia vs Alzheimer's: Signs, symptoms and preventing Alzheimer's disease with Lisa McGuire, PhD
Following National Alzheimer’s Disease Awareness Month, the CDC shares what physicians and patients need to know about the disease. Lisa McGuire, PhD, lead epidemiologist at the CDC, discusses the importance of catching Alzheimer’s early, its risk factors and barriers to make Alz ... Show More
13m 18s
Aug 2023
Monoclonal Antibodies Targeting Amyloid for Alzheimer Disease
<p>In this interview, dementia expert Gil D. Rabinovici, MD, discusses monoclonal antibodies that target beta-amyloid–-including a recent phase 3 trial of donanemab published in JAMA-–and reviews considerations for their use in patients with Alzheimer disease.<br /> <br /> <stron ... Show More
28m 48s
Nov 2023
Alzheimer’s Update, Part 2
This episode explores the current state of research on the multiple likely mechanisms of Alzheimer’s disease as well as promising treatments and diagnostics. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309944. 
54 m
Dec 2024
156| Updated Diagnosis and Staging Criteria for Alzheimer's Disease – A Conversation with Dr. Cliff Jack and Dr. Kevin Duff
<p class="MsoNormal">This episode is a conversation with Drs. Clifford Jack and Kevin Duff about recent updates to the diagnosis and staging of Alzheimer's disease (AD). We discuss biological versus clinical/pathological approaches to diagnosing AD, analogies between AD and other ... Show More
1h 44m