In this episodeof Neurology Today in 5, Neurology Today editor-in-chief Joseph E. Safdieh, MD, FAAN, discusses a large trial that found high-dose Vitamin D reduced MRI evidence of disease activity in patients with clinically isolated syndrome or early relapsing MS; an animal brain map, revealing changes in inflammation, immune activity, and cell repair that preceded the appearance of MS lesions; and a discussion of the challenges and opportunities of using AI in neurology education.