About this episode
Mar 18
Age Faster or Slower? The Surprising Role of Mental Health and Self-Control
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Terrie Moffitt, University Professor at Duke University. They explore the deep link between mental health, self-control, and the pace of biological aging, showing how early-life mental disorders can s ... Show More
1h 3m
Mar 4
Why Most Longevity Advice Gets Weight and Exercise Wrong
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Allison, Director of the USDA Children’s Nutrition Research Center at Baylor College of Medicine. Together, they examine what it takes to build public trust in nutrition and longevity science, a ... Show More
1h 10m
Feb 18
Can Psychedelic Mushrooms Slow Aging?
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Louise Hecker, Associate Professor of Medicine at Baylor College of Medicine. Together, they dive into Louise’s recent research exploring how psilocybin, the active compound in psychedelic mushrooms, ... Show More
52m 57s
Oct 2024
#320 – AMA 64: New insights on GLP-1 agonists (Ozempic, Wegovy, Mounjaro) - efficacy, benefits, risks, and considerations in the rapidly evolving weight-loss drug landscape
20m 36s
Sep 2024
Longevity Scientist Shares Top Strategies for Improving Your Health Span w/ Matt Kaeberlein, PhD
<p>Today's show is brought to you by MYOXCIENCE Nutrition. In this episode Matt Kaeberlein, PhD, CEO of Optispan, discusses the significance of enhancing health span through interventions like rapamycin and highlights the role of senescent cells in chronic inflammation and age-re ... Show More
1h 29m
Jul 2024
Zone 2 training: impact on longevity and mitochondrial function, how to dose frequency and duration, and more | Iñigo San-Millán, Ph.D. (#201 rebroadcast)
2h 46m
Sep 2025
#282 - Longevity biomarkers for healthy aging and well-being | Dr. Matt Kaeberlein & Mike Haney
Longevity is a hot health topic, but what factors move the needle on not only how long you live but how long you experience relatively good health? Some lab and other tests can help assess how healthy you’re aging and provide context for what lifestyle and other changes to make. ... Show More
1h 50m
Jun 2024
#305 ‒ Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
1h 51m
Sep 2025
Transform Your Metabolic Health & Longevity by Knowing Your Unique Biology | Dr. Michael Snyder
My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of ... Show More
2h 45m
Feb 2025
#336 - AMA #68: Fasting, well-balanced diets, alcohol, exercise for busy people, wearables, emotional health, assessing cardiovascular health, and more
27m 29s
Mar 2025
Understanding GLP-1: The Latest Research from WHOOP with Dr. Greg Grosicki
<p>Are GLP-1 medications the future of weight loss? On this week’s episode, WHOOP Global Head of Human Performance Principal Scientist, Kristen Holmes, sits down with Dr. Greg Grosicki, WHOOP Senior Research Scientist, to discuss all things GLP-1 and GLP-1 Receptor Agonists (RAs) ... Show More
48m 30s
Aug 2024
Enhancing Muscle Quality and Longevity | Dr. Anurag Singh
Discover the groundbreaking science behind healthy aging in this episode of the Dr. Gabrielle Lyon Show! Join Dr. Lyon as she sits down with Dr. Anurag Singh, an MD PhD with extensive research in immunology, to explore the incredible benefits of Urolithin A, a compound that's sho ... Show More
1h 31m
Jan 2025
#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller
2h 41m
Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular health, brai ... Show More
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