logo
episode-header-image
Mar 2025
28m 35s

Sir Magdi Yacoub on pioneering heart tra...

Bbc Radio 4
About this episode

What does it take to earn the nickname, ‘The Leonardo da Vinci of heart surgery’?

That's the moniker given to today's guest - a man who pioneered high-profile and often controversial procedures, but also helped drive huge medical progress; carrying out around 2,000 heart transplants and 400 dual heart-lung transplants during his 60-year career.

Sir Magdi Yacoub is Emeritus Professor of Cardiothoracic Surgery at Imperial College London, and Director of Research at Harefield Hospital’s Magdi Yacoub Institute. Inspired by a surgeon father and impacted by the tragic early death of his aunt from a heart condition, his medical career includes various surgical firsts alongside numerous research projects, to further our understanding of and ability to treat heart disease. He headed up the teams that discovered it is possible to reverse heart failure, and that successfully grew part of a human heart valve from stem cells for the first time.

But it hasn't always been plain sailing. At times, his work – such as early, unsuccessful transplant attempts, or using a baboon as a life-support system for a baby – attracted serious public criticism.

Speaking to Professor Jim Al-Khalili, Sir Magdi reflects on the highs and lows of his cardio career, and offers his advice to the next generation of surgeons and researchers hoping to make their mark in heart medicine.

Presented by Jim Al-Khalili Produced by Lucy Taylor

Up next
Oct 7
Mark O'Shea on close encounters with venomous snakes
How do you feel about snakes? What about highly venomous ones?For Mark O’Shea, close encounters with the world’s most rare and deadly snakes are not only his profession, but his passion. Mark is a Professor of Herpetology - the area of zoology focusing on reptiles and amphibians ... Show More
28m 28s
Jul 15
Kevin Fong on medical planning for Mars and Earth-based emergencies
There can't be many people in the world who've saved lives in hospital emergency rooms and also helped care for the wellbeing of astronauts in space – but Kevin Fong’s career has followed a singular path: from astrophysics and trauma medicine, to working with NASA, to becoming an ... Show More
28m 39s
Jul 8
Dame Pratibha Gai on training atoms to do what we want
Chemical reactions are the backbone of modern society: the energy we use, the medicines we take, our housing materials, even the foods we eat, are created by reacting different substances together. If we zoom in, it’s the atoms within these substances that rearrange themselves to ... Show More
28m 23s
Recommended Episodes
Sep 1
The Life Scientific: Sir Magdi Yacoub
What does it take to earn the nickname, ‘The Leonardo da Vinci of heart surgery’?That's the moniker given to today's guest - a man who pioneered high-profile and often controversial procedures, but also helped drive huge medical progress; carrying out around 2,000 heart transplan ... Show More
26m 29s
Oct 2024
The Surgeon Behind The World First Robotic Heart Transplant | Dr. Feras Khaliel 126
A surgeon at King Faisal Specialist Hospital and Research Center in Riyadh, Saudi Arabia, made history by performing the world’s first robotic heart transplant, an achievement that highlighted both the advancement of technology in the medical field showcasing the surgeon’s techni ... Show More
1h 16m
Feb 2025
Cardiology (THE HEART) with Herman Taylor
It beats. It throws blood. It breaks – but not if Dr. Herman Taylor can help it. He is a physician, professor and director of the Cardiovascular Research Institute at the Morehouse School of Medicine in Atlanta, and an absolute legend. Cardiology is a vast field but Dr. Taylor jo ... Show More
1h 21m
Aug 2024
Vasoplegia after cardiac surgery
Hypotension and shock are both recognized as complications post-cardiac surgery. Some patients may develop more severe shock refractory to fluids and catecholamines. This response is also known as today's podcast episode, topic: vasoplegia after cardiac surgery. For this discussi ... Show More
46m 11s
Aug 7
The Engineers: Exploring the human
Engineering has moved inside the body to innovate like never before. In neuro-science, brain implants can provide ‘psychic’ communication for people with locked-in syndrome. In medication a new technology aims to deliver chemo therapy and other drugs directly to the parts that ne ... Show More
49m 44s
Oct 2023
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a reco ... Show More
1h 50m
Aug 2024
The Life Scientific
Sir Jonathan Van-Tam, or ‘JVT’ as he's arguably better known, first came to widespread public attention in his role as Deputy Chief Medical Officer during the Covid-19 pandemic.But even before that, Jonathan had built an impressive career based on a long-held fascination with res ... Show More
27m 58s
Jun 2024
Rejuvenation through Stem Cells: Strategies for Longevity and Health - Episode 241
Welcome to the Gladden Longevity Podcast! In this episode, Host Steve Reiter and Dr. Jeffrey Gladden are joined by Christian Drapeau. Christian Drapeau is a renowned stem cell scientist and author with over 30 years of experience in medical research. He is best known for creating ... Show More
47m 14s
Mar 2022
223: Thoughts on Transplant Surgery
Today we talk to an abdominal transplant surgeon who's been practicing for 18 years in an Academic setting. Let's talk about their journey.Links:Full Episode Blog PostMeded MediaBlueprint MCATAmerican Society of Transplant Surgeons 
38m 1s
Nov 2024
Doctor Of The Future - Stem Cell Expert Explains Why Top Athletes Use Them! | Dr. Venkatesh | TRS
Check out my Mind Performance app: Level SuperMind Link:- https://install.lvl.fit/s6zb18o923q67pgfsgmdgm Share your guest suggestions here Link - https://forms.gle/aoMHY9EE3Cg3Tqdx9 Join the Level Community Here: https://linktr.ee/levelsupermindcommunity Check out BeerBiceps Skil ... Show More
2h 2m