logo
episode-header-image
Nov 2024
36m 11s

The Ecstasy of an Open Brain

Wnyc Studios
About this episode

As we grow up, there are little windows of time when we can learn very, very fast, and very, very deeply. Scientists call these moments, critical periods. Real, neurological, biological states when our brain can soak up information like a sponge. Then, these windows of learning close. Locking us in to certain behaviors and skills for the rest of our lives. But … what if we could reopen them? Today, we consider a series of discoveries that are reshaping our understanding of when and how we can learn. And what that could mean for things like PTSD, brain disease, or strokes. And cuddle puddles. It’s a mind-bending discussion. Literally and figuratively.

This is the second episode in an ongoing series hosted by Molly Webster, in conversation with scientists and science-y people, doing work at the furthest edges of what we know. You can find the first episode here. More to come! 

Special thanks to Gül Dölen, at the University of California, Berkeley, along with researcher Romain Nardou. Plus, Charles Philipp and David Herman.

We have some exciting news! In the “Zoozve” episode, Radiolab named its first-ever quasi-moon, and now it's your turn! Radiolab has teamed up with The International Astronomical Union to launch a global naming contest for one of Earth’s quasi-moons. This is your chance to make your mark on the heavens. Vote on your favorites starting in November: https://radiolab.org/moon

EPISODE CREDITS: 
Hosted by - Molly Webster
Reported by - Molly Webster
Produced by -Sindhu Gnanasambandan 
with help from - Timmy Broderick and Molly Webster
Original music and sound design contributed by - Dylan Keefe
with mixing help from - Jeremy Bloom
Fact-checking by - Emily Krieger
and Edited by  - Soren Wheeler

EPISODE CITATIONS:

Science Articles -

Gul’s 2019 paper: Oxytocin-dependent reopening of a social reward learning critical period with MDMA  (https://zpr.io/wfQjeA6PGCBv) on the feel-good brain chemical oxytocin, and how it reopens social reward learning when combined with MDMA.

Gul’s 2023 paper: Psychedelics reopen the social reward learning critical period (https://zpr.io/TKDKEwiLwGRN) on the role of psychedelics in social reward learning.
 

Sign-up for our newsletter. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!

Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.

Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.


Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

Up next
Oct 3
Adoptive Couple v. Baby Girl
This is the story of a three-year-old girl and the highest court in the land. The Supreme Court case Adoptive Couple v. Baby Girl is a legal battle that has entangled a biological father, a heart-broken couple, and the tragic history of Native American children taken from their f ... Show More
45m 29s
Sep 26
Voice
Over the course of millions of years, human voices have evolved to hold startling power. These clouds of vibrating air carry crucial information about who we are–and we rely on them to push ourselves up and out into the physical world.This week, we’re on a journey to understand h ... Show More
1h 6m
Sep 19
The Spark of Life
In the 1920s, a Russian biologist studying onion roots made a surprising discovery: underground, down in the darkness, it seemed like the cells inside the onion roots were making their own … light. The “onion root experiment” went on to become something of a cult classic in scien ... Show More
36m 1s
Recommended Episodes
Jun 2025
Talk Tracks Ep 11: Tom Campbell's Theory of Everything Explains Telepathy
What if consciousness—not matter—is the foundation of reality? In this episode of Talk Tracks, physicist and consciousness researcher Tom Campbell joins Ky Dickens to share his “Big Theory of Everything,” a model that unites quantum physics and spirituality by proposing that we a ... Show More
50m 13s
Jul 2018
Ketamine to Neurofeedback: The Brain Hacking Episode - David Feifel : 513
This podcast episode is all about the brain because the guest is master clinician, certified neuropsychiatrist, and brain scientist, Dr. David Feifel.Feifel founded the Kadima Neuropsychiatry Institute in San Diego after having been a professor of psychiatry at UC San Diego for m ... Show More
1h 18m
Sep 26
The Dead Composer Whose ‘Brain’ Still Makes Music
In a hauntingly innovative exhibit, brain cells grown from the late composer Alvin Lucier’s blood generate sound. Set in a museum in Perth, Australia, the installation blurs the line between art and neuroscience. Host Rachel Feltman and associate editor Allison Parshall explore t ... Show More
25m 25s
Sep 17
Talk Tracks Ep. 18: Transcendental Meditation and Consciousness
In this episode of Talk Tracks, neuroscientist and global leader of the Transcendental Meditation movement Dr. Tony Nader turns the question of consciousness upside down. Trained at Harvard and MIT, Dr. Nader once studied the brain as the source of awareness—until his research le ... Show More
37m 22s
Sep 12
Unpacking the Brain’s Role in Inventing Your Perception
Human brains don’t just perceive reality—they invent it. In this episode of Science Quickly, cognitive neuroscientist Daniel Yon speaks with host Rachel Feltman about how perception is an active process of prediction in which the brain constructs theories about the world that can ... Show More
15m 37s
Sep 19
Algorithmic Social Media Is Driving New Slang
From viral slang such as “skibidi” to the rise of so-called brain rot, linguist and content creator Adam Aleksic, aka the “Etymology Nerd,” and associate editor Allison Parshall, who covers the mind and brain, unpack how social media and algorithms are reshaping the way we commun ... Show More
26m 55s
Apr 2025
From the Internet’s Beginnings to Our Understanding of Consciousness, This Editor Has Seen It All
Senior mind and brain editor Gary Stix has covered the breadth of science and technology over the past 35 years at Scientific American. He joins host Rachel Feltman to take us through the rise of the Internet and the acceleration of advancement in neuroscience that he’s covered t ... Show More
20m 15s
Mar 2025
Oprah and Harvard Professor Share How Psychedelics Are Actually Healing
BUY THE BOOK! “How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence” by Michael Pollan “Fire in the Hole!: The Untold Story of My Traumatic Life and Explosive Success” by Bob Parsons In this ... Show More
57m 47s
Aug 6
Dr. Joe Dispenza
Dr. Joe Dispenza is an author, researcher, and lecturer whose work bridges neuroscience, epigenetics, and quantum physics to explore the science of personal transformation. Known for books like New York Times bestseller You Are the Placebo, Breaking the Habit of Being Yourself, a ... Show More
2h 20m
Mar 2025
M. Chirimuuta, "The Brain Abstracted: Simplification in the History and Philosophy of Neuroscience" (MIT Press, 2024)
This book is available open access here. The Brain Abstracted: Simplification in the History and Philosophy of Neuroscience (MIT Press, 2024), Mazviita Chirimuuta argues that the standard ways neuroscientists simplify the human brain to build models for their research purposes mi ... Show More
50m 44s