We revisit a topic covered previously as part of our “Heme/Onc Emergencies” series: heparin-induced thrombocytopenia (HIT) in Episode 017. As part of our return, we dive deeper into the pathophysiology, principles of diagnosis, and management of HIT to help you to better understand how to approach the question of “is this HIT?” as a Hematology consultant and ... Show More
Sep 23
Episode 165: CLL Updates Series, Pt. 2 – Relapsed/Refractory in 2026
This week we wrap up our two-part CLL update by turning to relapsed and refractory disease. We pick up with the 68-year-old man from Part 1, now a year out from frontline therapy and showing signs of relapse. We cover when relapse actually needs treatment, the history of BTK inhi ... Show More
22m 22s
Sep 16
Episode 164: CLL Updates Series, Pt. 1 – Frontline Therapy in 2026
This week we kick off a two-part update to our CLL series, covering what has changed in frontline management since our original episodes. Using the case of a 68-year-old man with newly diagnosed, symptomatic CLL, we revisit the essential steps before treatment: confirming an indi ... Show More
26m 2s
Sep 9
Episode 163: Head and Neck Cancer Series, Pt. 5 – Recurrent, Relapsed, and Metastatic Disease
This week the Head and Neck series turns to what happens when local therapy isn't enough — recurrent, relapsed, and metastatic disease. Using the case of a woman with a laryngeal cancer recurrence, we work through the first and most important question (recurrence versus second pr ... Show More
29m 14s
Sep 2025
Immune Thrombocytopenia Purpura ( ITP) 2025 UPDATE
<p>This week’s episode will be focusing on Immune Thrombocytopenia Purpura ( ITP). We will go all the important details on causes, mechanism, diagnosis and treatment. The last time we covered this topic was in Sept 2022, and this comes up ALL the time in heme consults, and ther ... Show More
9m 8s
May 2022
148. In the Eye of the Storm - An Approach to Disseminated Intravascular Coagulation
Send us Fan MailIn this episode we review the pathophysiology, diagnosis, and approach to the patient with DIC. Listen closely for some key tips on diagnostic scores and the trap of an inappropriately normal fibrinogen! Written by: Dr. Stefan Jevtic (Internal Medicine Resident), ... Show More
11m 23s
Jan 2021
IBCC Episode 110 - Disseminated Intravascular Coagulation
In this episode, we cover disseminated intravascular coagulation. It sounds bad, because it is. Come listen and refresh your skills around supporting the bleed-bleedy versus the cloth-clotty, how to differentiate DIC and chronic liver failure and a few more juicy clinical pearls.
35m 16s
May 2024
24. Thrombocytopenia with Dr. Matthew Rendo
<p>Thrombocytopenia is a puzzling, yet common problem in the ambulatory setting, on the wards and certainly in critically ill patients! Having an understanding of why it matters, why it can happen and what we should do about it, is of paramount importance to you if you are c ... Show More
1h 38m
Mar 2023
187. Breaking down the perPLEXing topic of TTP
Send us Fan MailIn this episode, we discuss the clinical presentation, laboratory abnormalities, initial work-up and treatment of TTP. We review the pathophysiology and also how to distinguish TTP from other MAHAs based on the patient's lab findings and clinical presentation. The ... Show More
13m 54s