In this continuation of our myeloma series, we discuss the progression of MGUS & smoldering myeloma to multiple myeloma. We also outline how to risk stratify a patient with multiple myeloma and gauge their response to treatment.
Content:
-What is the natural progression from MGUS to smoldering myeloma to multiple myeloma?
- How do we risk stratify patients ... Show More
Oct 7
Episode 166: Pancreatic Cancer Series, Pt. 1 – Biology, Diagnosis, and Staging
This week we kick off a brand-new series on pancreatic cancer, starting with the fundamentals. Using the case of a 68-year-old man with painless jaundice, weight loss, and new-onset diabetes, we cover the epidemiology and sobering survival statistics of pancreatic ductal adenocar ... Show More
28m 52s
Sep 23
Episode 165: CLL Updates Series, Pt. 2 – Relapsed/Refractory in 2026
This week we wrap up our two-part CLL update by turning to relapsed and refractory disease. We pick up with the 68-year-old man from Part 1, now a year out from frontline therapy and showing signs of relapse. We cover when relapse actually needs treatment, the history of BTK inhi ... Show More
22m 22s
Sep 16
Episode 164: CLL Updates Series, Pt. 1 – Frontline Therapy in 2026
This week we kick off a two-part update to our CLL series, covering what has changed in frontline management since our original episodes. Using the case of a 68-year-old man with newly diagnosed, symptomatic CLL, we revisit the essential steps before treatment: confirming an indi ... Show More
26m 2s
May 2022
S1 Episode 1: Avoiding the Cliff: Screening for Early-Stage Multiple Myeloma
Joseph Mikhael, MD, and Irene Ghobrial, MD, discuss screening high-risk populations for early-stage multiple myeloma and new techniques to detect it. Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/viewarticle/964336). The t ... Show More
24m 2s
Jun 2022
S1 Episode 3: Addressing Comorbidities in Multiple Myeloma: Treating People, Not the Disease
Joseph Mikhael, MD, and Ashley Rosko, MD, discuss the role of comorbidities in multiple myeloma and stress the importance of shifting away from the sole use of age-based treatment decisions. Relevant disclosures can be found with the episode show notes on Medscape.com (https://ww ... Show More
20m 18s
Aug 2025
S2 Episode 1: Managing Side Effects and Maximizing Quality of Life in Multiple Myeloma Patients
Joseph Mikhael, MD, and Surbhi Sidana, MD, discuss the importance of balancing treatment intervals, managing side effects, and maximizing quality of life in multiple myeloma patients. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.c ... Show More
23m 58s
Sep 2025
S2 Episode 3: When Is the Best Time to Use CAR T-Cell Therapy in Multiple Myeloma?
Joseph Mikhael, MD, and Krina K. Patel, MD, MSc, discuss considerations for CAR T-Cell therapy in multiple myeloma, including age, access, and bridging therapy. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002715. ... Show More
24m 38s