Not to be confused with “carcinoma of unknown primary,” in this episode of metastatic disease of “origin TBD”, we discuss the workup of a mass noted incidentally on imaging. This is a very high yield topic often faced on solid oncology consults!
Major Points Covered:
Mass found incidentally on imaging → we need to stage always
Initial Workup:
Reasonable t ... Show More
Today
Episode 145: Myeloma Series, Pt. 6 - First line treatment of Multiple Myeloma (2026)
This week, we begin our discussion about treatment of multiple myeloma, focusing on the first-line setting. Once again, a lot has changed in this space over the last few years, most notably the standards of care (now quadruplet regimens instead of triplet regimens!). We break dow ... Show More
40m 27s
Jan 7
Episode 144: Myeloma Series, Pt. 5 - Myeloma Risk Stratification and Response Criteria (2026)
This week, we introduce a new episode for our myeloma series, this time focusing on risk stratification and response criteria. The initial workup and surveillance labs are expansive, but all of the studies we do have a purpose. Many present-day studies also use “minimal residual ... Show More
29m 16s
Dec 30
Episode 143: Myeloma Series, Pt. 4 - Myeloma Pharmacology (2025)
We bring back our prior pharmacology discussion because it’s so incredibly important for the conversations that are on the horizon over the next few weeks. In this continuation of our myeloma series, we begin our discussion about treatment options for multiple myeloma, focusing f ... Show More
48m 42s
Nov 6
Pancreatic and Hepatobiliary Cancer
Send us a textNinja Nerds!In this episode of the Ninja Nerd Podcast, Zach and Rob explore pancreatic and hepatobiliary cancers through four patient cases packed with clinical pearls.We begin with a 63-year-old man presenting with painless jaundice, pruritus, and weight loss. Zach ... Show More
36m 59s
Sep 2025
Episode 65. Circulating Tumor DNA in DLBCL with Dr. Ash Alizadeh and Dr. David Russler-Germain
In this episode of Blood Cancer Talks, hosts Eddie, Ashwin, and Raj welcome two distinguished experts to explore the cutting-edge field of circulating tumor DNA (ctDNA) in B-cell lymphomas. Dr. David Russler-Germain, a lymphoma clinician from Siteman Cancer Centre at Washington U ... Show More
53m 8s
Dec 2024
139. Back to Basics - Early HER2 Breast Cancer
<p>Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers, including breast, gastric, colorectal, and epithelial ovarian cancers. However, this receptor's complexity doesn't stop there. It has multiple subdomains and various responses to drugs, and t ... Show More
24m 31s
Mar 2023
S4 E9: "Do The Maths" song; JOMT interview - Dr Sam Merriel talks about prostate cancer; also antibiotic resistance, nitrofurantoin failure, kidney stones
Welcome to the Hot Topics Podcast with host, Dr Neal Tucker. In this bumper edition, we have the next in our Just One More Thing series. We interview Dr Sam Merriel in collaboration with Prostate Cancer UK, talking about what we need to know in the world of prostate cancer. Shoul ... Show More
40m 32s
Oct 23
Esophageal & Gastric Cancer
Send us a textNinja Nerds!In this episode of the Ninja Nerd Podcast, Zach and Rob discuss two high-yield, board-relevant cases highlighting the diagnosis, staging, and treatment of esophageal adenocarcinoma and intestinal-type gastric adenocarcinoma.We begin with a 56-year-old ma ... Show More
28m 56s
Dec 2024
141. Back to Basics - The role of endocrine therapy in Breast Cancer
<p>Before immunotherapy, targeted chemotherapy (ADCs) and precision oncology, there was endocrine therapy, the forefather (or mother) of effective treatment to reduce breast cancer recurrence as well as delay disease progression. This episode dives into a past of phenomenal impro ... Show More
24m 4s