Molecular Testing Pearls
In Part 4 of our Heme Path series, we thoroughly examine the details of molecular testing and how it relates to hematologic and oncologic malignancies
I. Molecular Testing Basics
A. Provides a means of assessing patient’s genotypes, specifically at smaller changes in the genetic information
B. How is it performed?
1. Polymerase ch ... Show More
Today
Episode 169: Pancreatic Cancer Series, Pt. 4 – Metastatic Disease
This week, we continue our Pancreatic Cancer series with the setting where most of our patients live: metastatic disease. Using our case of a patient with newly diagnosed metastatic pancreatic cancer, we trace how first-line chemotherapy evolved from single-agent gemcitabine to F ... Show More
33m 17s
Oct 14
Episode 167: Pancreatic Cancer Series, Pt. 2 – Resectable Disease
This week our pancreatic cancer series moves from diagnosis to management, starting with resectable disease. Using the case of a 68-year-old man with a 2.8 cm adenocarcinoma of the pancreatic head, we define what "resectable" actually means, review the operation and the goal of a ... Show More
26m 23s
May 2022
Acute Myeloid Leukemia (AML)
<p>Today’s episode is all about AML (acute myeloid leukemia), including the usual presentation, diagnostic work-up, risk stratification (and tricks to remember these), molecular testing, and treatment options for first-line, as well as relapsed/refractory disease.</p>
15m 18s
Apr 2023
Papers Unplugged: Precision Medicine and Myeloid Neoplasms
In this podcast, Hartmut Döhner, Hematologist-Oncologist and Professor of Medicine in Germany, discusses with Dr. Nathalie van Havre the role of genomic characterization in the classification, prognosis and treatment of myeloid neoplasms. Discover the main methods of genomic test ... Show More
14m 32s
Dec 2023
A natural history of familial platelet disorder with myeloid malignancy; HEXIM1 as an essential transcription regulator in erythropoiesis; residual disease predicts relapse in CML patients
In this week's episode we’ll discuss the findings from a natural history study of patients with familial platelet disorder with myeloid malignancy, learn more about the role of HEXIM1 as an essential transcription regulator in human erythropoiesis, and discuss the utility of resi ... Show More
21m 53s
May 2025
Measurable residual disease and maintenance therapy in acute myeloid leukemia (AML), stemness and chemotherapy resistance in AML, and effects of babesiosis on red blood cells in sickle cell disease
In this week's episode, we’ll learn more about how measurable residual disease might help guide decisions about post-transplant gilteritinib maintenance in FLT3-ITD acute myeloid leukemia, or AML; how stemness contributes to chemotherapy resistance in AML; and effects of babesios ... Show More
19m 58s
Feb 2025
Myeloproliferative Neoplasia
Send us Fan MailNinja Nerds!Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myeloproliferative Neoplasms, covering their pathophysiology, clinical presentation, and management. We discuss Polycythemia Vera, Essential Thrombocythemia, Chronic Myelo ... Show More
37m 25s