Molecular Testing Pearls
In Part 4 of our Heme Path series, we thoroughly examine the details of molecular testing and how it relates to hematologic and oncologic malignancies
I. Molecular Testing Basics
A. Provides a means of assessing patient’s genotypes, specifically at smaller changes in the genetic information
B. How is it performed?
1. Polymerase ch ... Show More
Today
Episode 145: Myeloma Series, Pt. 6 - First line treatment of Multiple Myeloma (2026)
This week, we begin our discussion about treatment of multiple myeloma, focusing on the first-line setting. Once again, a lot has changed in this space over the last few years, most notably the standards of care (now quadruplet regimens instead of triplet regimens!). We break dow ... Show More
40m 27s
Jan 7
Episode 144: Myeloma Series, Pt. 5 - Myeloma Risk Stratification and Response Criteria (2026)
This week, we introduce a new episode for our myeloma series, this time focusing on risk stratification and response criteria. The initial workup and surveillance labs are expansive, but all of the studies we do have a purpose. Many present-day studies also use “minimal residual ... Show More
29m 16s
Dec 30
Episode 143: Myeloma Series, Pt. 4 - Myeloma Pharmacology (2025)
We bring back our prior pharmacology discussion because it’s so incredibly important for the conversations that are on the horizon over the next few weeks. In this continuation of our myeloma series, we begin our discussion about treatment options for multiple myeloma, focusing f ... Show More
48m 42s
Mar 2025
Decoding Risk: Understanding Polygenic Risk Scores in Modern Medicine. Demystifying Genetics with Erica Spaeth
<p>This episode dives into polygenic risk testing, exploring how genetic data can inform healthcare strategies. We discuss the complexities of communicating risk, the role of polygenic scores in identifying disease susceptibility, and the evolving landscape of personalized medici ... Show More
49m 41s
Oct 3
Genetics: Gene Expression
In this episode, we explore key topics in genetics, including how sex-linked and autosomal traits are inherited. We'll break down inheritance patterns using real-world examples, like X-linked recessive diseases, and walk through Punnett square problems to show how these traits ar ... Show More
52m 43s
Jul 2024
Genetic Testing for Sports Performance
In this episode, I discuss genetic testing for sports and athletic performance. I describe the history of sports genomics and the search for genes that determine strength, endurance, and other performance markers. I explain how to interpret genetic test results, including how man ... Show More
1h 43m
Aug 2024
Episode 147: Genetic Mutation and Repair
Here we survey of the causes and consequences of genetic mutation, including a discussion of mechanisms of endogenous and induced mutations, rates of mutation, types of single nucleotide mutations, and the phenotypic effects of mutation. We also discuss various mechanisms for det ... Show More
1h 13m
Apr 2024
Switzerland, AI and Liquid Biopsies
AI and predictive modeling to understand an individual’s immune system function and predict treatment response are still in very early stages. We dream about precision medicine and getting every answer we can for ourselves when we get sick. However, if we look at genomics, only a ... Show More
36m 51s
Sep 2025
Episode 65. Circulating Tumor DNA in DLBCL with Dr. Ash Alizadeh and Dr. David Russler-Germain
In this episode of Blood Cancer Talks, hosts Eddie, Ashwin, and Raj welcome two distinguished experts to explore the cutting-edge field of circulating tumor DNA (ctDNA) in B-cell lymphomas. Dr. David Russler-Germain, a lymphoma clinician from Siteman Cancer Centre at Washington U ... Show More
53m 8s
May 2025
Behaviors That Alter Your Genes to Improve Your Health & Performance | Dr. Melissa Ilardo
My guest is Dr. Melissa Ilardo, Ph.D., professor of biomedical informatics at the University of Utah. We discuss the interplay between genes and behaviors, including how certain behaviors can improve resilience by changing gene and organ function, as well as natural selection eve ... Show More
1h 54m
Sep 2024
Episode 200: Immune Checkpoint Inhibitors
We discuss a new class of medications, Immune Checkpoint Inhibitors, and their side effects. Hosts: Avir Mitra, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Immune_Checkpoint_Inhibitors.mp3 Download Leave a Comment Tags: Oncology Show Notes Ov ... Show More
13m 26s
Nov 2024
Cancer Cells Gone Wild: Real Biology Exposed
In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss the complexities of cancer with Dr. Joe Zundell, a cancer biologist. They explore the definition of cancer, its prevalence, and the hallmarks that characterize cancer cells. The conversation delves into the mecha ... Show More
59m 38s