Anaphylaxis is a severe, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway and/or breathing and/or circulation problems usually associated with skin and mucosal changes. Adriana Andreae, Assistant Professor, Department of Pediatrics Division of Allergy and Immunology, Penn State University, gives us an overview of the condition. For more on anaphylaxis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000099 -

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