In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse this proc ... Show More
Mar 2026
What Houses, Garbage, and Trucks Teach Us About Aging with Dr. Uri Alon
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Uri Alon, Professor at Weizmann Institute of Science. They explore a systems view of aging that treats longevity as a solvable model, not a grab bag of disconnected theories.Uri explains aging with a ... Show More
1h 4m
Mar 2026
Born to Live Longer? Inside the Genetics and Biology of Centenarians
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Paola Sebastiani, Professor of Biostatistics at Tufts Clinical and Translational Science Institute. They explore what centenarians reveal about reaching 100, and why there’s no single longevity gene.P ... Show More
1h 1m
Dec 2021
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
In this episode, I am joined by Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. Dr. Sinclair is also the author of the book Lifespan: Why We Age & Why We Don't Have To, and the host of the Lifespan Po ... Show More
2h 7m
Sep 2019
#70 - David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
<p>In this episode, David Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, returns to the podcast to discuss the content of his new book, Lifespan: Why We Age - ... Show More
2h 10m
Oct 2025
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair
In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, reg ... Show More
39m 7s
Sep 2019
We Can Slow Down Aging Right Now – David Sinclair, Ph.D. : 626
<p>In this episode of Bulletproof Radio,my guest is an Australian biologist best known for his research on lifespan extension and the treatment of diseases for aging.</p><p>“I'm a scientist,” says David Sinclair, Ph.D., “and I'm trying to figure this stuff out before time ru ... Show More
1h 11m
Nov 2022
How to Live Longer (and Better) | David A. Sinclair, Ph.D.
<p>Question for you: what if you could slow down, stop or even reverse your aging process? What if you could live, not just longer, but better? Extending and even potentially expanding your physical and mental health and well-being. Staving off decline or illness. Is any of that ... Show More
1h 4m