Jul 30

Metformin as an adjunctive therapy to an intensive lifestyle intervention in older adults with obesity with Dennis Villareal

Metformin has received a lot of attention in the field of ageing, though clinical trials remain scarce. Dennis Villareal (Michael E. DeBakey VA Medical Center, Houston, USA) discusses the DEMFOS trial assessingl assessing whether adding metformin to an intensive lifestyle interve ... Show More

13m 44s

Jun 2025

Ara Nazarian on musculoskeletal diseases in the USA

The burden of musculoskeletal diseases is increasing. Dr Ara Nazarian tells us more about the issues surrounding this and how care can be improved in the USA.Read the full paper:https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00026-1/fulltext?dgcid=buzzsprout_ic ... Show More

7m 58s

Apr 2025

Andrew Kingston on socioeconomic inequalities and disability

Socioeconomic status impacts the onset and duration of severe disabilities, but what does this means for public health policy? Andrew Kingston (Newcastle University, UK) talks to Editor-in-Chief of The Lancet Healthy Longevity Philippa Harris about his study on socioeconomic ineq ... Show More

35m 8s

Jul 2022

Talk Evidence - shoulders, knees, and woes

In this episode, Juan Franco, editor in chief of BMJ EBM, and Helen Macdonald, The BMJ's research integrity editor, sit down to discuss what's new in the world of evidence. Firstly, last week they went to the first EBM Live conference for two years - and report back on what happ ... Show More

37m 45s

Jul 2021

The Bio-Chemistry of Life - An interview with Dr. Dayan Goodenowe PhD - Episode 98

Today's show rundown: Short Telomeres in relation to COVID 19 Jeff talks more about telomeres and where you can find info Mark introduces today's guest Dr. Dayan Goodenowe Dr. Goodenowe talks a little about what he does and how he got started Fun ... Show More

1h 10m

Jun 2023

Focus - How We Age Well

Why are some of us more susceptible to dementia? What is a 'Super Ager'? And what might help us protect our brains in later life? In this focus episode of How We’re Wired join producer Dr Eva Higginbotham as she dives into the science of Super Agers, from the genes that increase ... Show More

19m 23s

Mar 2025

Localisation myths, brain fog, and small fibre neuropathies - Editors' Highlights April 2025

It's a podcast of pairs this time, for the latest issue of the journal. There's two hosts, two halves of the brain, two sides to a clinical debate, and two themes to the episode itself. Leading off is a discussion on peripheral neurology, taking a look at the editors' choice p ... Show More

42m 52s

Mar 2024

Jaimie Steinmetz, Theo Vos, Katrin Seeher and Tarun Dua on the global burden of disorders affecting the nervous system

Jaimie Steinmetz and Theo Vos from the Institute for Health Metrics and Evaluation, and Katrin Seeher and Tarun Dua from WHO, join Heather Brown and Lauren Southwell to discuss new data on the global, regional, and national burden of disorders affecting the nervous system. The Ar ... Show More

26m 11s

Nov 2024

Genetic Leukodystrophies Mimicking CNS Inflammation - Part 2

In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment ... Show More

13m 12s

Sep 2023

An Updated Round Table Discussion on FND: Sharing a Diagnosis and Treatment

In the last episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about diagnosis and treatment for FND. Related Links: FND Society at <a href="fndsociety.org" target="_blank" rel= "noopen ... Show More

21m 30s

Jan 2025

98. Meningitis Masterclass

Jame and Callum are joined by Dr Fiona McGill, lead author of the 2016 Joint Specialist Societies Meningitis Guidelines.Listen to hear an overview of the epidemiology, presentation, diagnosis and management of both bacterial and viral meningitis in the UK. Show notes for this epi ... Show More

1h 7m

Jun 2024

Mortality in a Danish NMO Cohort

Dr. Justin Abbatemarco talks with Prof. Zsolt Illes about the mortality of patients with AQP4 antibody–seropositive neuromyelitis optica spectrum disorder compared with that in the general population. Read the related article in Neurology. This podcast is sponsored by argenx. Vi ... Show More

18m 40s

Sep 2024

Neuroimaging in the Era of Anti-Amyloid Therapies - Sponsored by GE HealthCare

Dr. Linda Chu speaks with Dr. Giuseppe Esposito, Dr. Yasar Torres-Yaghi, and Dr. Lydia Wood to explore how the availability of amyloid PET imaging and other advanced neuroimaging techniques is transforming the diagnostic and treatment landscape for neurodegenerative disorders. Sp ... Show More

50m 15s

Juan Fortea on biomarkers of neurodegene...