Electroconvulsive therapy is highly effective in treating major depressive disorder, but no one knows why it works. New research suggests it may restore balance between excitation and inhibition in the brain.
Jan 27
Is Particle Physics Dead, Dying, or Just Hard?
Particle physics hasn't yet found the new physics needed to resolve its deepest mysteries. It’s hard to know what to think about or look for. But the most devoted particle physicists are thinking and looking all the same. On this episode, host Samir Patel and columnist Natalie Wo ... Show More
26m 24s
Jan 20
Does Dad's Fitness Make Its Way Into Sperm?
We already know that what we eat, drink, and inhale can affect which parts of our DNA are expressed, and which aren’t. But recent research poses a shocking idea: A dad’s habits may be encoded in molecules and transmitted to his future kids. On this episode, host Samir Patel and b ... Show More
32m 24s
Sep 2024
The sweeping reorganisation of the brain in pregnancy, and why it matters
Ian Sample talks to Dr Laura Pritschet, a postdoctoral fellow of psychiatry at the University of Pennsylvania, about her research using precision scans to capture the profound changes that sweep across the brain during pregnancy. She explains what this new work reveals about how ... Show More
14m 25s
Nov 2024
Anneli Jefferson, "Are Mental Disorders Brain Disorders?" (Routledge, 2024)
The question of whether mental disorders are disorders of the brain has led to a long-running and controversial dispute within psychiatry, psychology and philosophy of mind and psychology. While recent work in neuroscience frequently tries to identify underlying brain dysfunction ... Show More
1h 25m
Sep 2021
TU156: What Actually Heals in Therapy with Psychoanalyst Nancy McWilliams – Replay
For todays’ replay, we thought it would be a great opportunity to revisit our conversation with renowned psychoanalyst and psychologist, Nancy McWilliams. It can be difficult to verbalize the issues with “evidence-based” models of care, but with McWilliam’s deeper analysis of qua ... Show More
45m 44s
Aug 2024
Ketamine's antidepressant effect, and bee brains find a way
In the news podcast, could Chinese scientists have found the mechanism that gives ketamine its antidepressant effect? Also, how a Cambridge researcher has laid the foundations for eliminating a form of blindness in English Shepherd dogs, and how bees find their way about with rem ... Show More
29m 33s
May 2025
Essentials: Understanding & Healing the Mind | Dr. Karl Deisseroth
In this episode of Huberman Lab Essentials, my guest is Dr. Karl Deisseroth, M.D., Ph.D., a clinical psychiatrist and professor of bioengineering and of psychiatry and behavioral sciences at Stanford University. We discuss his experiences as a clinician treating complex psychiatr ... Show More
44 m