A couple of weeks ago, Charlie Marsh and the folks at Astral made another big splash with a major release of uv called "uv: Unified Python packaging" which has many far reaching features. We had to have Charlie on the show to give us the inside look into this development. Let's get to it.
Apr 27
#546: Self hosting apps for Python people
The cloud is convenient until it isn't. You upload your photos, sync your contacts, click through the cookie banners. Then prices go up again or you read about a family that lost their entire Google account over a medical photo sent to a doctor. At some point, the question shifts ... Show More
1h 3m
Apr 16
#545: OWASP Top 10 (2025 List) for Python Devs
The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Tanya Janca is back on Talk Python to walk us through every single one of them. And we're not just talking theory, we're going to turn Claude ... Show More
1h 6m
Aug 2025
911: The Future of Python Notebooks is Here, with Marimo’s Dr. Akshay Agrawal
Reproducibility, Python notebooks, and data science communities: Software developer Akshay Agrawal speaks to Jon Krohn about Marimo, the next-generation computational notebook for Python, how he built and fostered a thriving community around the product, and what makes this noteb ... Show More
58m 20s
Jun 2018
Python at Microsoft (Interview)
We talked with Steve Dower and Dan Taylor at Microsoft Build 2018 about the history of Python at Microsoft, the origination of IronPython, Python Tools for Visual Studio, flying under the radar to add support Python, fighting from within to support open source, and more.
37m 51s
Aug 2025
Live from Big Sky Dev Con: Code Debates, Content Insights, and What's Next for Web Development
Live from Big Sky Dev Con, Robbie is joined by Aaron Francis, Ken Wheeler, and Typecraft to discuss HTML and CSS programming status, React’s future, app security failures, NPM’s weak spots, content creation hooks, survival tech fantasies, and balancing big tech ambitions with fam ... Show More
50m 55s
Sep 2024
Late Night Linux – Episode 299
Learning undergraduate level signal processing for free, a few more uses for KDE Connect, analysing audio for HiFi setups, deep inspection of Python objects, viewing HTTP archives, and more on the problem with micropayments. Discoveries Signal Processing Course KDE Connect Fritur ... Show More
23m 12s
Nov 2016
Python, Django, and Channels (Interview)
Django core contributor Andrew Godwin joins the show to tell us all about Python and Django. If you've ever wondered why people love Python, what Django's virtues are as a web framework, or how Django Channels measure up to Phoenix's Channels and Rails' Action Cable, this is the ... Show More
1h 15m
Sep 2022
Ambient Mesh, with Justin Pettit and Ethan Jackson
<p>When you think of a service mesh, you probably think of "sidecar containers running with each pod". The Istio team has come up with a new approach, introduced recently as an experimental preview. Google Cloud software engineers <a href= "https://twitter.com/Justin_D_Pettit">Ju ... Show More
55m 48s