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Sep 2024
2m 41s

Preventing HIV with antiretrovirals - Tr...

John Bennett, MD / Henry Masur, MD
About this episode

A 58-year-old HIV- negative gay man is evaluated for PrEP. His past medical history is notable for hypertension, treated for over 10 years with an ACE inhibitor. He is asymptomatic and weighs 145 lbs.


He is sexually active with multiple partners but “usually” practices safe sex.


Lab studies reveal: HIV 4th generation test negative, HIV-1 RNA negative, CBC normal, creatinine 1.4 with a

calculated creatinine clearance of 48 ml/min.


What do you recommend for PrEP?

A. No PrEP

B. Tenofovir disoproxil fumarate/emtricitabine 1 pill daily

C. Tenofovir disoproxil fumarate/emtricitabine 1 pill every other day

D. Tenofovir alafenamide/emtricitabine 1 pill daily


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