Every year the core developers meet to discuss and propose the major changes and trends in Python itself. This invite-only conference of about 50 people happens inside PyCon in the US. Because it's private, we rarely get detailed looks inside this event. On this episode, we have Seth Michael Larson here to give us his account of the sessions and proposals. I ... Show More
Jan 23
#535: PyView: Real-time Python Web Apps
Building on the web is like working with the perfect clay. It’s malleable and can become almost anything. But too often, frameworks try to hide the web’s best parts away from us. Today, we’re looking at PyView, a project that brings the real-time power of Phoenix LiveView directl ... Show More
1h 7m
Jan 13
#534: diskcache: Your secret Python perf weapon
Your cloud SSD is sitting there, bored, and it would like a job. Today we’re putting it to work with DiskCache, a simple, practical cache built on SQLite that can speed things up without spinning up Redis or extra services. Once you start to see what it can do, a universe of poss ... Show More
1h 14m
Jan 5
#533: Web Frameworks in Prod by Their Creators
Today on Talk Python, the creators behind FastAPI, Flask, Django, Quart, and Litestar get practical about running apps based on their framework in production. Deployment patterns, async gotchas, servers, scaling, and the stuff you only learn at 2 a.m. when the pager goes off. For ... Show More
1h 1m
Aug 2025
911: The Future of Python Notebooks is Here, with Marimo’s Dr. Akshay Agrawal
Reproducibility, Python notebooks, and data science communities: Software developer Akshay Agrawal speaks to Jon Krohn about Marimo, the next-generation computational notebook for Python, how he built and fostered a thriving community around the product, and what makes this noteb ... Show More
58m 20s
Jun 2018
Python at Microsoft (Interview)
We talked with Steve Dower and Dan Taylor at Microsoft Build 2018 about the history of Python at Microsoft, the origination of IronPython, Python Tools for Visual Studio, flying under the radar to add support Python, fighting from within to support open source, and more.
37m 51s
Nov 2016
Python, Django, and Channels (Interview)
Django core contributor Andrew Godwin joins the show to tell us all about Python and Django. If you've ever wondered why people love Python, what Django's virtues are as a web framework, or how Django Channels measure up to Phoenix's Channels and Rails' Action Cable, this is the ... Show More
1h 15m
Feb 2022
Modern Code Generation with Jordan Adler
<p>Jordan Adler is Head of Developer Engineering at OneSignal and has a deep interest in code generation. He has helped migrate large systems from Python 2 or Python 3 using code generation and code transformation. Using tools like Yellicode, Python Future, and others, Jordan's t ... Show More
34m 49s
Nov 2024
833: The 10 Reasons AI Projects Fail, with Dr. Martin Goodson
Martin Goodson speaks to Jon Krohn about what he would add to his viral article “Ten Ways Your Data Project is Going to Fail”, why practitioners always need to be present at AI policy discussions, and Evolution AI’s breakthroughs in computer vision and NLP.
This episode is broug ... Show More
1h 25m
Jun 2023
AI trends: a Latent Space crossover
Daniel had the chance to sit down with @swyx and Alessio from the Latent Space pod in SF to talk about current AI trends and to highlight some key learnings from past episodes. The discussion covers open access LLMs, smol models, model controls, prompt engineering, and LLMOps. Th ... Show More
59m 39s
Feb 2025
Sam Altman's Wild 2035 Prediction
<p>OpenAI CEO Sam Altman just dropped a new blog post outlining his vision for AGI, AI economics, and the next decade. His key prediction? By 2035, any individual will have access to as much intelligence as the world today. Is this realistic, or just more hype? This episode break ... Show More
22m 16s
Aug 2025
Live from Big Sky Dev Con: Code Debates, Content Insights, and What's Next for Web Development
Live from Big Sky Dev Con, Robbie is joined by Aaron Francis, Ken Wheeler, and Typecraft to discuss HTML and CSS programming status, React’s future, app security failures, NPM’s weak spots, content creation hooks, survival tech fantasies, and balancing big tech ambitions with fam ... Show More
50m 55s