Join Drs Benjamin Schlechter and Jeff Meyerhardt as they discuss the latest breakthroughs in adjuvant chemo for CRC and share their decision-making in real-world scenarios.
Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1000093. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Colorectal Cancer: Prevention, Diagnosis, and Therapeutic Options https://reference.medscape.com/slideshow/colorectal-cancer-6007241
Colon Cancer https://emedicine.medscape.com/article/277496-overview
Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer https://pubmed.ncbi.nlm.nih.gov/15175436/
Duration of Adjuvant Chemotherapy for Stage III Colon Cancer https://pubmed.ncbi.nlm.nih.gov/29590544/
Overall Survival With 3 or 6 Months of Adjuvant Chemotherapy in Italian TOSCA Phase 3 Randomised Trial https://pubmed.ncbi.nlm.nih.gov/33098997/
3 Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Combination Therapy for Colorectal Cancer (SCOT): An International, Randomised, Phase 3, Non-Inferiority Trial https://pubmed.ncbi.nlm.nih.gov/29611518/
Randomized Phase III Study of Capecitabine Plus Oxaliplatin Compared With Fluorouracil/Folinic Acid Plus Oxaliplatin as First-Line Therapy for Metastatic Colorectal Cancer https://pubmed.ncbi.nlm.nih.gov/18421053/
Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials https://pubmed.ncbi.nlm.nih.gov/36306483/
Impact of Age on the Efficacy of Newer Adjuvant Therapies in Patients With Stage II/III Colon Cancer: Findings From the ACCENT Database https://pubmed.ncbi.nlm.nih.gov/23733765/
Comparative Effectiveness of Oxaliplatin vs Non-Oxaliplatin-Containing Adjuvant Chemotherapy for Stage III Colon Cancer https://pubmed.ncbi.nlm.nih.gov/22266473/
Role of Physical Activity and Diet After Colorectal Cancer Diagnosis https://pubmed.ncbi.nlm.nih.gov/25918293/
Association of Dietary Patterns With Cancer Recurrence and Survival in Patients With Stage III Colon Cancer https://pubmed.ncbi.nlm.nih.gov/17699009/
Irinotecan Fluorouracil Plus Leucovorin Is Not Superior to Fluorouracil Plus Leucovorin Alone as Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803 https://pubmed.ncbi.nlm.nih.gov/17687149/
Feasibility and Acceptability of a Physical Activity Tracker and Text Messages to Promote Physical Activity During Chemotherapy for Colorectal Cancer: Pilot Randomized Controlled Trial (Smart Pace II) https://pubmed.ncbi.nlm.nih.gov/35014958/