This past week marked the passing of the great pediatric cardiology pioneer, Dr. Sylvia Griffiths. Dr. Griffiths was a trainee of Dr. Ruth Wittemore of Yale University and was one of the founders of the pediatric cardiology program at NY Presbyterian Hospital in the mid 1950's with Dr. Sidney Blumenthal. Her career spanned 7 decades, all at NY Presbyterian, Columbia University. She is remembered as a pioneering woman in medicine as well as a pioneer as a pediatric cardiologist. She is also remembered as a kind and warm colleague and friend. In today's 304th episode of Pediheart we review a 55 year old paper by Dr. Griffiths on outcomes of partial AV canal repair and speak with the present chief of pediatric cardiology at NY Presbyterian, Dr. Christopher Petit about the important role she played at Columbia. We then speak with Professor of Pediatrics at the Albert Einstein College of Medicine, Dr. Christine Walsh about the role she played in Dr. Walsh's life as well as the lives of so many patients, colleagues and friends. Her imprint will remain and she will always be missed and remembered fondly by all.